logo
episode-header-image
Oct 2024
1h 21m

Don’t Die with Bryan Johnson : 1211

Dave Asprey
About this episode

Today, we’re unlocking the full potential of your brain—starting with Bryan Johnson’s Blueprint for longevity and brain optimization. 

We’re revisiting our conversation with Bryan, the creator of the Don’t Die movement (among many other things), to explore how his groundbreaking approach to brain health and biohacking is reshaping the future of longevity. 

First, we dive into Bryan’s mission to make brain monitoring as easy as tracking blood glucose, using his Blueprint protocol to measure and optimize cognitive performance for better health and wellness. 

Then, we tackle the deeper side of biohacking—longevity, societal reactions to living longer, and how to handle critics when you’re pushing the limits of human potential. 

Finally, Bryan shares his personal journey—investing $80M into brain science, building the Blueprint for optimal living, and discovering the power of community and lifelong friendships for a long, vibrant life. This episode will change the way you think about brain health and the future of humanity. 


Sponsors


Resources


Timestamps and Highlights

00:00 Introduction and Bold Claims 

00:39 Meet Bryan Johnson: The Neuroscience Pioneer 

01:23 Kernel: Revolutionizing Brain Measurement 

05:51 Biohacking and Longevity 

07:30 Facing Criticism and Staying Resilient 

16:06 Media Training Insights 

19:49 Personal Reflections and Relationships 

34:37 Exercise and Longevity 

44:46 Optimizing Brain-Body Interface 

45:25 Longevity Hacks and Driving Preferences 

45:48 Debating Olive Oil and Saturated Fats 

46:52 The Blueprint Approach to Health 

48:38 Testing and Metrics in Health 

52:22 Testosterone and Hormone Protocols 

56:27 Exploring Semen Retention 

01:00:44 Body Hair and Aesthetics 

01:04:26 Psychedelics and Consciousness 

01:08:32 Audience Q&A and Final Thoughts 

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Up next
Oct 7
The Hidden Key to Pain-Free Joints (Longevity Tips) : 1341
Most people think about heart disease and metabolism when they talk about longevity, but too few talk about joint health. In this episode, you’ll discover how to biohack your joints to prevent pain, reverse damage, and move like you’re decades younger. Host Dave Asprey reveals ho ... Show More
1h 2m
Oct 5
Remote Work Is Making You FATTER (Do THIS to Stop It) : 1340
Remote work might feel like freedom, but your biology disagrees. In this video, I break down how your work-from-home setup is hijacking your hormones: crushing testosterone, spiking cortisol, and wrecking insulin sensitivity. I’ll show you exactly how posture, light, movement, an ... Show More
14m 5s
Oct 3
10-Minute Weekly Update : 1339
Upgrade your week in just 10 minutes with D(AI)ve Asprey’s essential rundown on what matters most in longevity, biohacking, AI health tech, and medical freedom. This episode covers: • Apple Cider Vinegar Myth Busted A weight-loss study just got retracted. ACV will not melt fat, b ... Show More
10m 17s
Recommended Episodes
Mar 2025
Do you want to die? How Bryan Johnson plans to cheat death
Could optimizing your sleep significantly extend your lifespan? In this episode, we dive deep into the science of longevity with Bryan Johnson, the entrepreneur spending millions to reverse aging, and Professor Tim Spector, one of the world’s top 100 most-cited scientists and an ... Show More
1h 6m
Jan 2025
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep
Do you think one bad night of sleep can really harm your body? Would you try a routine that could help you reverse aging? Today, Jay sits down with Bryan Johnson, entrepreneur and founder of Blueprint, who is redefining human health and longevity. Dubbed "the world's most measure ... Show More
1h 28m
Jun 2025
Don't Die by Bryan Johnson Book Summary and Review
Show notes⁠ / Don't Die is more than just another health book. It mixes philosophy with science. Johnson sees aging as a disease we can beat. Read 1 million books in minutes. For free. Get the PDF, infographic, extended ad-free audiobook and animated version of this summary and u ... Show More
26m 52s
Apr 2024
My Doubts About Bryan Johnson’s “Never Die” Protocol
Bryan Johnson began his life as an entrepreneur, buying, selling, and growing companies like Venmo to build a healthy living for himself. Several years ago, he became fascinated with the idea of maximizing human technology to extend the length and quality of one's life as far ... Show More
1 h
Dec 2024
123. Dr. Peter Diamandis: The Future of Health with Stem Cells, Blood Filtration, & AI
What if you could become biologically 20 years younger in just 12 months? According to Dr. Peter Diamandis, XPRIZEFoundation founder and author of the “Longevity Guidebook,” we’re closer than you think. In this episode, Dr. Peter Diamandis reveals why 2024 marks the beginning of ... Show More
1h 17m
Jan 2025
E073 - The Anti-Aging Routine That Actually Works (Biohacking Guide) | Dave Asprey
This week, I’m joined by the father of biohacking, Dave Asprey. The pioneer behind the global movement that has transformed the way people optimise their health and performance. With decades of experience in biohacking, Dave has authored multiple bestsellers and founded companies ... Show More
1h 44m
Sep 1
5 Minutes to Longevity & Younger Brain (Science of REHIT) with Ulrich Dempfle
What if you could get twice the health and brain benefits of traditional cardio in just five minutes?I know, it sounds impossible. Most people think they need to spend 45 minutes on a treadmill to see real results, but the science shows otherwise.In today’s episode, I’m diving in ... Show More
19m 56s
Sep 5
Most Replayed Moment: This Longevity Protocol Actually Works! - Biohacker Bryan Johnson
Bryan Johnson is a tech entrepreneur, longevity researcher, and founder of Blueprint - a project to reverse his biological age through rigorous data, diet, and discipline. Known as one of the world’s most committed biohackers, Johnson lives by a strict protocol involving 111 pill ... Show More
20m 20s
Sep 29
Andrew Huberman: The #1 Reason Why Faith-Based Practices Matter When It Comes To Your Mental Health
The world's most respected neuroscientist just admitted something LIVE at Summit of Greatness that shocked everyone: prayer saved his mental health. After decades of relying purely on science, Andrew Huberman discovered that faith-based practices don't just feel good—they literal ... Show More
58m 11s
Sep 11
200. 200th Episode of the #1 Health Podcast in the World! - Dana White, Joe Rogan, RFK Jr. & More!
200 episodes ago, I had a simple dream: put life-changing information on a platform for free, and watch humanity transform. Today, that vision has created the world’s leading health and wellness podcast, featuring conversations with RFK Jr. outlining his $1.9 trillion plan to end ... Show More
24m 40s