Could optimizing your sleep significantly extend your lifespan?
In this episode, we dive deep into the science of longevity with Bryan Johnson, the entrepreneur spending millions to reverse aging, and Professor Tim Spector, one of the world’s top 100 most-cited scientists and an expert in nutrition and the microbiome.
Bryan has dedicated his life—and his b ... Show More
Yesterday
5 ways relationships change your gut health | Prof Tim Spector
Are modern habits around cleanliness, parenting, and social contact shaping your gut health more than you realise? In this episode, Professor Tim Spector explains how gut microbes are shared between people - through relationships, daily contact, and the environments we live in, a ... Show More
51m 58s
Jan 29
4 lifestyle changes that lower high blood pressure | Dr Sanjay Gupta
High blood pressure is the number one risk factor for deaths globally. But what if your blood pressure numbers were only part of that story? In this episode, we’re joined by leading cardiologist Dr Sanjay Gupta, who explains why blood pressure is not a disease, but often a scream ... Show More
55m 32s
Jan 2025
Bryan Johnson: New SHOCKING Science on How to Reverse Your Age by 31 Years & The Damaging Impact of 1 Bad Night Sleep
Do you think one bad night of sleep can really harm your body? Would you try a routine that could help you reverse aging? Today, Jay sits down with Bryan Johnson, entrepreneur and founder of Blueprint, who is redefining human health and longevity. Dubbed "the world's most measure ... Show More
1h 28m
Sep 2024
Longevity Scientist Shares Top Strategies for Improving Your Health Span w/ Matt Kaeberlein, PhD
<p>Today's show is brought to you by MYOXCIENCE Nutrition. In this episode Matt Kaeberlein, PhD, CEO of Optispan, discusses the significance of enhancing health span through interventions like rapamycin and highlights the role of senescent cells in chronic inflammation and age-re ... Show More
1h 29m
Aug 2025
190. Is Spermidine The Solution To Slow Down Cellular Aging?
Scientists tracked 829 people for 20 years and discovered that one “embarrassingly named” nutrient, Spermidine, reduced death rates by nearly 40%. This polyamine doesn’t just slow aging, it literally stabilises your DNA and activates cellular repair pathways that tell your cells ... Show More
9m 7s
May 2025
Advice From the #1 Longevity Doctor: Add 10 Years to Your Life With 3 Simple Habits
<p>Today’s episode could change (or save) your life. It’s a must-listen. </p><p>You’ll hear from the world’s leading longevity doctor about the simple, proven changes that will help you live longer, feel better, and prevent diseases like cancer, heart disease, and dementia. </p>< ... Show More
1h 7m
Feb 2025
How Long Can Humans Live? Insights from Dr. Jay Olshansky
<p>In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Jay Olshansky, a leading professor at the University of Illinois Chicago and a renowned expert in aging and biodemography. Together, they delve into the science of longevity, exploring how public health ... Show More
1h 10m
Nov 2024
How To Replace Exercise, Heat, Cold & Fasting With Pharmaceuticals (WARNING: Proceed At Your Own Risk!) With Dr. Sandra Kaufmann
In today’s episode, you’ll get to explore the cutting-edge world of anti-aging and longevity with Dr. Sandra Kaufmann, a leader in cellular optimization. Dr. Kaufmann guides you through affordable ways to understand your genetic traits, dives into the brain-boosting benefits of l ... Show More
56m 58s
Dec 2024
125. Kristen Holmes: WHOOP’s Principal Scientist Reveals Game-Changing Research
Could sleep consistency, not duration, be the hidden key to elite performance? In this conversation with WHOOP's Global Head of Performance & Science, Kristen Holmes, we uncover revolutionary findings that are reshaping our understanding of sleep science. Together, we dive deep i ... Show More
1h 9m
Oct 2023
2182: From Adversity to Model Health With Shawn Stevenson
In this episode Sal, Adam & Justin speak with Shawn Stevenson, author of Sleep Smarter, Eat Smarter, and the new Eat Smarter Family Cookbook. Learning along the way as a parent. (2:29) "Life doesn't call the qualified. Life qualifies the called." (5:50) We are a product of our en ... Show More
1h 57m
Feb 2025
745. Want To Age Backwards? Dr. Mark Hyman on Fad Diets, Longevity + Inflammation
In this episode, Lindsey sits down with Dr. Mark Hyman to uncover the interconnection of diet, inflammation, and chronic disease. They also get into the nitty-gritty of balancing Western and Eastern medicine to live longer, healthier, and happier lives!
Ahead, Lindsey shares he ... Show More
1h 19m