Host Dave Asprey and Dylan Gemelli explore peptides, research chemicals, and SARMs, breaking down what actually works, what carries risk, and why reclaiming medical autonomy is central to optimizing human performance, metabolism, and longevity.
Feb 8
Why Your Muscles Break Down After 40 (Do This To Reverse It) : 1412
Your muscles play a far bigger role in aging than most people realize. As you get older, the energy factories inside your muscle cells begin to break down and stop getting replaced, leading to fatigue, weakness, and slower recovery even if you stay active.This video explains how ... Show More
10m 16s
Feb 6
Biohackers in the Epstein Files, Generic GLP-1s, Continuous Ketone Monitors, and more... : 1411
This episode covers: • Longevity Influence In The Epstein Files A new DOJ document release tied to the Epstein investigation pulled physician and longevity influencer Peter Attia into the spotlight, after reports showed he appeared in the files more than 1,800 times and CBS News ... Show More
7m 11s
Feb 5
Why 18-Year-Olds Wake Up Fresh (And You Don't) : 1410
18-year-olds wake up fresh because their repair system still works. This episode shows you how stem cell decline quietly drives fatigue, inflammation, and faster aging, and how fasting can reactivate your body’s natural ability to repair itself without expensive stem cell procedu ... Show More
58m 50s
Feb 2022
Science Advisor Resigns, COVID Drug Treatments, Science Drag Artists. Feb 11, 2022, Part 1
<p>An Abrupt Departure For Biden’s Science Adviser</p>
<p>This week, Eric Lander, the Presidential science advisor and head of the Office of Science and Technology Policy, <a href="https://www.sciencefriday.com/segments/eric-lander-resignation/?utm_source=wnyc&utm_medium=podcast& ... Show More
53m 30s
May 2023
CRISPR | The Future of Genetic Engineering
<p>In this episode, Dr Matt and Dr Mike discuss how humans realised that bacteria could fight off viruses using sequences in their DNA called, CRISPR. Today, CRISPR technology is being used to cure cancer and investigate the cause of genetic disease. </p><br><p>For a video o ... Show More
1h 22m
Aug 2025
How AI could generate new life-forms | Eric Nguyen
If DNA is just a string of letters, could AI learn to read it … or even write it? Bioengineering researcher Eric Nguyen reveals how AI has upended the rules of biology, potentially creating a future where disease is cured with personalized medicine, extinct species are resurrecte ... Show More
13m 5s
Mar 2025
The Science, Evolution, and Future of Lifespan and Healthspan with Dr. Michael Ringel
<p>On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource alloc ... Show More
1h 12m
May 2023
Stefan Lorenz Sorgner, "We Have Always Been Cyborgs: Digital Data, Gene Technologies, and an Ethics of Transhumanism" (Bristol UP, 2023)
The concept of transhumanism emerged in the middle of the 20th century, and has influenced discussions around AI, brain–computer interfaces, genetic technologies and life extension. Despite its enduring influence in the public imagination, a fully developed philosophy of transhum ... Show More
42m 35s
Dec 2024
How to Use Curiosity & Focus to Create a Joyful & Meaningful Life | Dr. Bernardo Huberman
In this episode, my guest is Dr. Bernardo Huberman, Ph.D., a research physicist, expert on quantum networks, and vice president of CableLabs’ Next-Gen Systems. We discuss his journey into science, beginning in South America, how a curiosity about physics led him to the United Sta ... Show More
3h 15m
Jul 2025
Joyce Harper, PhD - The New Science of Creating Life
How far can we push our biology? Meet Joyce Harper, an internationally renowned, award-winning scientist and Professor of Reproductive Science at University College London, Institute for Women’s Health. Joyce has worked in the fields of fertility, genetics, reproductive health an ... Show More
53m 14s
