May 2024
14m 27s
A new study finds insulin resistance and reduced glucose uptake in the heart is linked with early-onset atherosclerosis and heart issues.
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Link to Video and Research: https://bit.ly/3UXLhal
Research Mentioned:
Devesa, A. et al. Cardiac Insulin Resistance in Subjects With Metabolic Syndrome Traits and Early Subclinical Atherosclerosis. Diabetes Care 46, 2050–2057 (2023).
Time Stamps:
00:00 FDG = Fluorodeoxyglucose
00:30 Reduced glucose uptake in the heart is tethered to atherosclerosis.
01:20 LDL levels are not strongly associated with poor outcomes.
02:00 Your heart becomes insulin resistant.
03:05 Those with no glucose uptake in the heart had higher fasting glucose.
03:45 Those with more cardiovascular risk factors had lower LDL.
04:35 The heart can generate energy from fatty acids, carbs, and ketones.
05:00 Cardiac abnormalities are associated with metabolic syndrome.
07:00 Insulin resistance changes muscle and heart muscle.
09:16 Insulin resistance is associated with a progressive decrease of myocardial FDG uptake.
09:50 Cardiovascular risk increases with the decline of FDG uptake.
11:30 Your heart loses the ability to pump blood effectively as it loses ability to utilize different energy substrates.
12:40 Support your heart by supporting your metabolism.