In this episode, I am joined by Dr. David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. Dr. Sinclair is also the author of the book Lifespan: Why We Age & Why We Don't Have To, and the host of the Lifespan Podcast, which launches January 5, 2022.
In this interview, we discuss the cellul ... Show More
Aug 21
Essentials: Timing Light for Better Sleep, Energy & Mood | Dr. Samer Hattar
In this Huberman Lab Essentials episode, my guest is Dr. Samer Hattar, PhD, the Chief of the Section on Light and Circadian Rhythms at the National Institute of Mental Health. We discuss how light powerfully shapes mood, sleep, appetite, learning and overall mental health by alig ... Show More
35m 19s
Aug 18
Using Stem Cells to Cure Autism, Epilepsy & Schizophrenia | Dr. Sergiu Pașca
My guest is Dr. Sergiu Pașca, MD, professor of psychiatry and behavioral sciences at Stanford University. We discuss the biology and genetics of autism, why autism diagnoses are increasing and recent progress in using stem cells to understand and treat profound autism and other b ... Show More
2h 23m
Aug 14
Essentials: Controlling Your Dopamine for Motivation, Focus & Satisfaction
In this Huberman Lab Essentials episode, I explain how dopamine regulates motivation and provide science-based tools to help improve focus, discipline and overall drive. I explore how particular activities affect dopamine levels and discuss how the highs, lows and baseline levels ... Show More
38m 37s
Jan 2022
The Science Behind Why We Age | Episode 1
In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process o ... Show More
1h 2m
Jan 2022
NMN, NR, Resveratrol, Metformin & Other Longevity Molecules | Episode 4
In this week’s episode, Dr. David Sinclair and co-host Matthew LaPlante zero in on drugs and supplements that have been reported to combat aspects of aging. They share the latest experimental and clinical data for NAD boosters, resveratrol, fisetin, quercetin, rapamycin, spermidi ... Show More
1h 10m
Jan 2022
What to Eat & When to Eat for Longevity | Episode 2
In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss how frequently we should eat, what food we should avoid, and what food we should pursue. They discuss the science behind how a "low energy state," which can be induced by a period of fasting, combats aging a ... Show More
1h 7m
Dec 2017
#040 Dr. Eric Verdin on Ketogenic Diet Longevity, Beta-Hydroxybutyrate & HDAC Inhibitors
Eric M. Verdin Eric M. Verdin, M.D. is the fifth president and chief executive officer of the Buck Institute for Research on Aging and is a professor of Medicine at UCSF. Dr. Verdin's laboratory focuses on the role of epigenetic regulators in the aging process, the role of metabo ... Show More
1h 3m
Apr 2020
The Science of Age Reversal | David A. Sinclair, Ph.D.
What if you could reverse the aging process? Sounds like science fiction, but the new science of aging is turning it into science fact. Today, we learn the truth about aging and how to potentially slow, stop and even reverse it from one of the world's leading voices in the scienc ... Show More
1h 4m
Feb 2022
The Science of Looking Younger, Longer | Episode 6
In Episode 6 of the Lifespan podcast, Dr. David Sinclair and co-host Matthew LaPlante discuss cosmetic aging and how to improve skin, nails, and hair. They talk about why superficial aging occurs and how external signs of aging are often a reflection of biological age. The latest ... Show More
1h 9m
Jan 2022
Exercise, Heat, Cold & Other Stressors for Longevity | Episode 3
In Episode 3 of the Lifespan Podcast, Dr. David Sinclair and Matthew LaPlante dive deeply into the science of non-dietary interventions that mimic adversity and promote health. They begin by highlighting how different types of physical activity (i.e., low-intensity aerobic exerci ... Show More
1h 11m