In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process of "ex-differentiation" in which cells begin to lose their identity, and how all ... Show More
May 6
What To Do For Longevity | Lifespan with Dr. David Sinclair Rewind
What are the most important things you can do today to live longer and stay healthier while doing it? In this first Lifespan Rewind episode, Dr. David Sinclair, A.O., Ph.D., a Professor of Genetics for over 25 years at Harvard Medical School and a leader in the field of longevity ... Show More
59m 10s
Feb 2022
Biotracking, Age Reversal & Other Advanced Health Technologies | Episode 8
In the final episode of this season, Dr. David Sinclair and Matthew LaPlante focus on current and near-future technologies relevant to health and aging. In addition to discussing the utility of wearable sensors and biological age measurements, they highlight innovative research a ... Show More
1h 9m
Dec 2021
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
In this episode, I am joined by Dr. David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. Dr. Sinclair is also the author of the book Lifespan: Why We Age & Why We Don't Have To, and the host of the Lifespan Po ... Show More
2h 7m
Sep 2019
#70 - David Sinclair, Ph.D.: How cellular reprogramming could slow our aging clock (and the latest research on NAD)
<p>In this episode, David Sinclair, Ph.D., a Professor in the Department of Genetics at Harvard Medical School and co-Director of the Paul F. Glenn Center for the Biological Mechanisms of Aging, returns to the podcast to discuss the content of his new book, Lifespan: Why We Age - ... Show More
2h 10m
Dec 2021
The Emerging Science Of Longevity with Peter Diamandis
This episode is brought to you by BiOptimizers, Athletic Greens, and Rupa Health. What if I told you we’ll reach a point in time where scientific breakthroughs will extend our lives by more than a year, for every year we are alive? This is called longevity escape velocity, and so ... Show More
1h 17m
Sep 2019
We Can Slow Down Aging Right Now – David Sinclair, Ph.D. : 626
<p>In this episode of Bulletproof Radio,my guest is an Australian biologist best known for his research on lifespan extension and the treatment of diseases for aging.</p><p>“I'm a scientist,” says David Sinclair, Ph.D., “and I'm trying to figure this stuff out before time ru ... Show More
1h 11m
Oct 2022
Why We Grow Old And How To Age Well
This episode is brought to you by Rupa Health, ButcherBox, and InsideTracker. In Western culture, we’ve gained a negative view of aging. But in other cultures around the world, aging is celebrated and embraced. That’s because we define difficult symptoms like aches and pains, cog ... Show More
59 m