logo
episode-header-image
Nov 2024
1h 8m

Your Brain On... Sex

Drs. Ayesha and Dean Sherzai
About this episode

From the first spark of attraction, all the way to climax, sex sets off chemical fireworks in your brain.

And yet, this beautiful, powerful act has become mired in shame and stigma. But through open conversation and deeper scientific understanding, we can cast off those shackles, and even embrace sex as a marker for cognitive and overall health.

In this episode of ‘Your Brain On...’ — our Season 4 debut! — we discuss:

• The neurological processes involved with sex, arousal, attraction, and desire • Why studying the cognitive effects of sexual stimuli can be so complicated • How our relationship with sex is altered as we age, and is affected by periods of change like menopause • The neuroscientific differences between masturbation and sex with a partner • The complex debate about pornography consumption, and the need for better sex education • The links between brain health, heart health, mental health, and sexual health • The benefits of good nutrition, exercise, and stress management for sexual health • Motivations and methods for freeing conversations about sex from stigmas and taboos — especially for women

Joining us for this immensely important conversation are two fantastic guests: sexual behaviour expert and data scientist Dr. Nicole Prause, and sexual medicine expert and urogynecologist Rena Malik.

This is... Your Brain On Sex.

‘Your Brain On’ is hosted by neurologists, scientists and public health advocates Ayesha and Dean Sherzai.

‘Your Brain On... Sex’ • SEASON 4 • EPISODE 1 (SEASON 4 DEBUT)

LINKS

Dr. Nicole Prause at UCLA: https://www.uclahealth.org/departments/medicine/gastro/research/labs-and-programs/patel-laboratory

Dr. Nicole Prause on Twitter: https://x.com/nicolerprause

Dr. Nicole Prause on Bluesky: https://bsky.app/profile/nicolerprause.bsky.social

Dr. Rena Malik’s website: https://renamalikmd.com/

Dr. Rena Malik on YouTube: https://www.youtube.com/@RenaMalikMD

Dr. Rena Malik on Instagram: https://www.instagram.com/renamalikmd/

FOLLOW US

Join the NEURO Academy: NEUROacademy.com

Instagram: @thebraindocs

Website: TheBrainDocs.com

More info and episodes: TheBrainDocs.com/Podcast

 

Up next
Yesterday
Your Brain On... Alzheimer’s (Mythbusting Special)
Alzheimer’s disease is constantly surrounded by myths and misinformation. Let’s set the record straight. In this episode, we bust through the most persistent Alzheimer’s myths, with facts based on decades of clinical experience and cutting-edge research. Myths include: • “Alzheim ... Show More
50m 4s
Jun 25
Your Brain On... Purpose (Sherzai Family Special)
With big changes happening in the Sherzai family household, we sat down for a roundtable discussion about the concept that will shape what we’re all doing next: our purpose. In this ‘unplugged’ mid-season chat, we’re joined by our kids — Sophia and Alex! — for a wide-ranging conv ... Show More
34m 8s
Jun 18
Your Brain On... Creatine
Creatine for Alzheimer’s — let’s separate the hype from the hope. A new study has caused a stir in June 2025, but lead researcher Matthew K. Taylor told us: “ I don’t think I can recommend it to a patient that this is going to ultimately have some sort of cognitive influence.” We ... Show More
49m 47s
Recommended Episodes
Sep 2024
Sexual Mastery with the World’s Top Experts: Unlocking Pleasure, Performance, and Intimacy : 1204
In this transformative episode of The Human Upgrade, three of the world’s foremost experts on sexual wellness—Kim Anami, Susan Bratton, and Emily Morse—explore the depths of sexual mastery, pleasure, and performance. This discussion uncovers the often-overlooked power of sexual e ... Show More
1h 1m
Mar 2025
This Is Your Brain on 2025: The Biohacker’s Guide to Mental Clarity & Mood | Dr. Drew Ramsey : 1263
You think you’re optimizing your brain—but what if the real culprit behind your brain fog, anxiety, and burnout is the modern world itself? In this episode, Columbia University psychiatrist and nutritional neuroscience pioneer Dr. Drew Ramsey joins Dave Asprey to decode the biolo ... Show More
1h 11m
Feb 2025
Episode 370: The Science of Sexual Pleasure
How do you define sexual pleasure? For some people, it simply means orgasm. But orgasm isn’t the only way we derive pleasure from sex! In this episode, we’re going to dive into the many and varied forms of sexual pleasure that exist, common barriers to experiencing pleasure, and ... Show More
40m 3s
Aug 2024
Ep. 140: Mutual Masturbation: A Masterclass
Send us a Text Message.In this episode we dive deep into the world of mutual masturbation — a topic often shrouded in misunderstanding and societal taboos. Discover the true essence of this intimate act, its surprising benefits for enhancing sexual connection, and how to introduc ... Show More
15m 43s
Jan 2024
Episode 257: How To Make a Sex Plan for the New Year (Essential Listen)
New year, new sex life. The transition between years is always a good time to stop and reflect, and that includes thinking about your intimate life. How are things going? Are you getting what you want? Does it feel like something is missing? Depending on how you answered these qu ... Show More
28m 29s
Oct 2024
Episode 336: Not Having Sex Is The Latest Sex Trend
A growing number of people seem to be hitting the pause button on their sex lives, which is why terms like “volcel” (short for voluntary celibacy) and “boysober” are trending on social media. So what’s this all about? Why is not having sex the hot new sex trend? Let’s talk about ... Show More
35m 30s
Nov 2024
Episode 348: How To Stay Sexually Healthy Your Entire Life
Our sexuality is something that evolves and changes over time. However, traditional sex education does a poor job of preparing us for those changes. In today’s show, we’re going to talk about how to stay sexually healthy for your entire life. We’re going to explore what people at ... Show More
33m 34s
Jul 2024
#1 SEX Doctor: For Better Orgasms Do THIS, Less Sex Can Be Better, Dr Karen Gurney
Follow to help grow our incredible community! In this episode of "Exhibit A," Abbey Clancy delves into the complexities of sex and relationships withThe Sex Doctor, Dr. Karen Gurney, a leading clinical psychologist and psychosexologist.  Dr. Gurney has over 20 years of experience ... Show More
1h 32m
Jul 2024
Ep. 137: 50 Shades of Play: Unmasking BDSM
Send us a Text Message.Today we will delve into the intriguing and often misunderstood world of BDSM. Whether you are a seasoned kinkster or just a curious cat, this episode will unravel the mysteries behind bondage, discipline, dominance, submission, sadism, and masochism.  We w ... Show More
16m 38s
Nov 2024
The Key To Happiness w/ Dr. Amen
What if being happy was a moral obligation, like voting and recycling? Would you take steps to be happier? Today, I’m joined by brain health expert, and New York Times best-selling author Dr. Daniel Amen to talk about how our thinking patterns shape our lives in and outside of th ... Show More
42m 49s