logo
episode-header-image
Jul 2024
1h 15m

The impact of ketones on performance and...

Gil Blander PhD
About this episode

In this episode of Longevity by Design, hosts Ashley Reaver and Dr. Gil Blander welcome Dr. Brianna Stubbs, an expert in exogenous ketone metabolism. Dr. Stubbs shares her journey from being a competitive rower to becoming a scientist. She dives into her research on ketone biology and its implications for health and aging.


Dr. Stubbs discusses the science behind ketones, explaining how they serve as an alternative fuel for the brain and body, particularly during periods of low carbohydrate intake. She highlights the potential benefits of ketones for cognitive function and heart health, noting their ability to act as signaling metabolites that influence oxidative stress and inflammation.


The conversation also explores the practical applications of ketone supplements for athletes and the general public. Dr. Stubbs emphasizes the importance of personalized approaches to diet and supplementation, considering individual goals and health conditions. She provides insights into her ongoing research at the Buck Institute, aiming to translate scientific discoveries into practical tools for healthy aging.


Up next
Aug 20
What Happens to Your Body When You Sit All Day, with Dr. Keith Diaz
In this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Keith Diaz, Associate Professor of Behavioral Medicine at Columbia University Irving Medical Center, to unpack the hidden health risks of prolonged sitting.Keith explains why even daily exercise isn't enou ... Show More
1h 5m
Aug 6
Acetylation Insights: Unlocking Longevity Secrets with Dr. Haim Cohen
In this episode, Dr. Gil Blander welcomes Dr. Haim Cohen to Longevity by Design to explore his revolutionary approach to understanding aging. Haim's team analyzed acetylation sites across 107 mammalian species, creating its most extensive comparative study. This computational app ... Show More
55m 51s
Jul 23
Karl Pfleger Explains the Aging Biotech Explosion
On this episode of Longevity by Design, Dr. Gil Blander sits down with Dr. Karl Pfleger, aging biotechnology investor and creator of AgingBiotech.info, to dissect the rapidly evolving field of aging therapeutics. Karl breaks down the sector into two main categories: interventions ... Show More
1h 18m
Recommended Episodes
Jan 2025
Feed Your Microbiome to Support Your Hormones (& Poop) with Colleen Cutcliffe Ph.D
Colleen Cutcliffe explores the microbiome's role during menopause, focusing on the estrobolome and gut bacteria's interaction with estrogen. She emphasizes the importance of gut health, particularly Acromantia, and discusses the negative impacts of birth control pills and antibio ... Show More
59m 29s
Jul 2024
The Heavy Metal You've Never Heard of: Deuterium's Impact on Metabolic Health, How to Avoid It and Deplete It with Dr. Sara Pugh | Episode 196
TODAY'S GUESTDr. Sara Pugh has a background in genetics, biochemistry and biophysics and has worked on protein folding, dopamine receptors, membrane proteins  genetic promoters in moss, statins & heart cells . She later trained in hypnosis ,  functional movement, functional ... Show More
1h 20m
Jul 14
Ketones for Metabolic Health, Brain Function, & Fertility with Latt Mansor
Latt Mansor explores the multifaceted role of ketones, particularly their influence on brain health, fertility, memory, and focus. The re-release of an episode from 2023 delves into their impact on serotonin receptors, blood glucose regulation, and weight management. Mansor also ... Show More
1h 11m
Jul 2024
Dr. Peter Attia: Supplements for Longevity & Their Efficacy
In this episode, my guest is Dr. Peter Attia, M.D., a Stanford and Johns Hopkins School of Medicine-trained physician expert in improving human healthspan and lifespan. Dr. Attia is also the host of The Drive podcast and author of the best-selling book Outlive. We discuss the NAD ... Show More
2h 30m
Aug 2024
Enhancing Muscle Quality and Longevity | Dr. Anurag Singh
Discover the groundbreaking science behind healthy aging in this episode of the Dr. Gabrielle Lyon Show! Join Dr. Lyon as she sits down with Dr. Anurag Singh, an MD PhD with extensive research in immunology, to explore the incredible benefits of Urolithin A, a compound that's sho ... Show More
1h 31m
Aug 2024
Strength Training to Cardio: A Comprehensive Movement Plan with Dr. Stacy Sims
Dr. Stacy Sims shares her insights on menopause, exercise, and nutrition for women. She underscores the importance of strength training, high-intensity workouts, and balancing cardio for women in perimenopause and postmenopause. Dr. Sims also elaborates on the key factors like sl ... Show More
1h 9m
Jul 21
Powering cellular energy and healthy ageing: behind the hype of NAD, NMN and NR supplements
Have you heard any of the buzz about NAD supplements? NAD is a molecule found in nearly every cell and sits at the heart of energy production and DNA repair. Our levels of NAD though can decline with age which has led to the idea that this could be one cause of many age-related d ... Show More
12m 42s
Nov 2024
Revolutionizing Women's Health: Protein, Menopause & Skeletal Muscle | Dr. Jamie Baum | Dr. Jaime Baum
Dive into an extraordinary conversation with Dr. Gabrielle Lyon and Dr. Jamie Baum, Associate Professor and Director of the Center for Human Nutrition at the University of Arkansas. In this episode, we explore revolutionary topics:The role of skeletal muscle in appetite regulatio ... Show More
1h 40m
Sep 2024
Navigating Perimenopause: Metabolic Health, Brain Fog & Belly Fat with Dr. Carrie Jones
Dr. Carrie Jones returns for another insightful episode on perimenopause and menopause, focusing on hormonal shifts starting around age 35. She discusses metabolic health, the role of lifestyle changes, intermittent fasting, protein intake, strength training, and the importance o ... Show More
1h 8m
Mar 2025
The Science of Midlife Fat Gain: Hormones, Insulin & GLP-1 with Dr. Ben Bikman
Dr. Ben Bikman explores blood sugar, weight loss, and hormonal health, sharing his expertise on how blood sugar imbalances contribute to chronic diseases. He clarifies the weight loss process, focusing on glucose, ketones, and GLP-1 hormones, particularly for women in midlife. Be ... Show More
1h 1m