Protein is essential for maintaining muscle mass as we age. Modulating protein intake via dietary intake or fasting can have variable effects on aging and muscle growth. Whereas fasting
turns off multiple pathways associated with aging, such as mTOR, IGF-1, growth hormone, and others, eating for optimal fitness activates these important processes. In this aliquot, we discuss:
- (00:00) Introduction
- (02:57) Growth-longevity trade-off (Mike Maser discussion)
- (11:45) Role of IGF-1 in the aging process (Valter Longo discussion)
- (12:55) mTOR and the IGF-1 regulation by amino acids (Peter Attia discussion)
- (15:55) Anti-cancer effect of glutamine restriction outweigh the negative effect of glutamine deprivation on the gut and liver (Dominic D’Agostino discussion)
- (22:45) The possibility of using selective nutrient restriction as an autophagy-inducer (Guido Kroemer discussion
- (26:23) The IGF-1 Trade-Off: Performance vs. Longevity (Rhonda Patrick discussion)
You can see the original full interview with Dr. Kroemer You can see the original full interview with Dr. D'Agostino You can see the original full interview with Dr. Attia You can see the original full interview with Rhonda Patrick (with Mike Maser) You can see the original full interview with Dr. Longo You can see the video featuring Dr. Rhonda Patrick here Get more Aliquots! Become a FMF Premium member and get full access to our members-only podcast, The Aliquot, plus live Q&As with Rhonda, biweekly Science Digest emails, and more.
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