logo
episode-header-image
About this episode

On this episode of the podcast, I discuss my approach and strategies to handle grapefruit juice interactions.

Grapefruit juice causes drug interactions by inhibiting the CYP enzyme system. More specifically, it inhibits CYP3A4 which is responsible for the breakdown of many medications.

Quantity is always an important consideration when assessing grapefruit juice interactions. The more that is taken, typically, the more drug concentrations will be affected.

It is important to assess the use of grapefruit juice when your patient has a history of cardiovascular disease, cardiac conditions, pain, mental health disease, or gout as some medications used to treat these diseases can interact with grapefruit juice.

If you are looking for more content on drug food interactions, be sure to check out my book in the links below.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

Flippin’ Pharmacology Flash Cards

Pharmacology Crossword Puzzle Book (Over 2,000 Clues/Questions!)

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Up next
Aug 21
Vilazodone Pharmacology
Vilazodone (brand name Viibryd) is an antidepressant with a unique pharmacologic profile compared to most other agents in the SSRI class. While not a first-line choice for every patient, understanding its mechanism, adverse effects, and interaction profile is essential for optimi ... Show More
13m 49s
Aug 14
Solifenacin Pharmacology
Solifenacin is a bladder antimuscarinic medication most commonly used for overactive bladder (OAB) with symptoms of urinary frequency, urgency, and urge incontinence. Like other agents in its class, understanding the pharmacology can help anticipate potential side effects, drug i ... Show More
12m 1s
Aug 7
Itraconazole Pharmacology
In this episode, we break down itraconazole—a potent antifungal with a lot of baggage. If you’re a pharmacist, clinician, or student who needs to understand how this drug works and why it can be tricky to use, this episode is for you. We start with the basics. Itraconazole blocks ... Show More
10m 50s
Recommended Episodes
Jan 2022
Turn Anxiety into Productivity and Grapefruit Juice vs. Meds
Dr. Wendy Suzuki explains how to use anxiety to your advantage. Plus: why grapefruit juice and some medicines don’t mix.More from Dr. Wendy Suzuki:Pick up “Good Anxiety: Harnessing the Power of the Most Misunderstood Emotion” https://www.simonandschuster.com/books/Good-Anxiety/We ... Show More
16m 51s
Nov 2023
The 5 Most Overrated Supplements
In this episode, Nurse Doza explored the often overlooked aspects of popular supplements. We discussed why certain supplements like Vitamin B12, probiotics, digestive enzymes, protein shakes, and DHEA might not always be the best choice for everyone. We emphasized the importance ... Show More
33 m
Jul 2022
Is Pharmacology Difficult Podcast ATROPINE & ALTERNATIVE DRUGS/SUBSTITUTES-3
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.In today's eye to eye talk, I show a great concern for your eyes and describe the Effects and Uses of Atropine and Congener drugs/ Substitute drugs on Eyes and associated structures. I will be covering Atropi ... Show More
10m 53s
Oct 2021
Cutting back on sugar? Here’s why fruit should stay on the menu
With all the recent health focus on sugar, poor old fruit has gotten undeserved attention for the simple reason that it is high in sugar. And from that, some very average advice has surfaced that people need to limit how much whole fruit they eat. Now a systematic review puts to ... Show More
7m 33s
Aug 2022
Is Pharmacology Difficult Podcast ATROPINE & ALTERNATIVE DRUGS/SUBSTITUTES-4
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.In today's episode, I will be discussing effects and applications of Anticholinergic drugs- Atropine and congener drugs on Sweating and also on Genitourinary system.To begin with, effects on sweating will be ... Show More
9m 8s
Oct 2022
#361 Advanced Lipidology
Lipids Update 2022: Cardiovascular Risk Reduction and New Medications on the Horizon with Erin Michos, MD Show description:  Ready to take the next step in management of your patient with hyperlipidemia? Dr. Erin Michos (@erinmichos) returns to give us a lesson in Advanced Lipido ... Show More
1h 18m
May 2022
Dr. Will Bulsiewicz On All Things Microbiome: Heal Your Gut, Sidestep Disease & Thrive
One of the most popular guests in the history of this podcast, Dr. Will Bulsiewicz ‘Dr. B' joined me back on episode #538 for a deep dive on the gut and honing our immune systems. Today we dive even deeper with a comprehensive investigation of the microbiome, why it’s important, ... Show More
3h 3m
Nov 2022
The 5 Flashcards You Need to Ace Pharmacology
Pharmacology is hands down one of the toughest classes you will take in nursing school. In this episode I'm sharing my personal study system for how to minimize your time studying and maximize the results. One of the main components of this system is the Fundamental Five Fla ... Show More
11m 5s
Oct 2022
Oct 28 2022 This Week in Cardiology
ERASE AF follow-up, recreational drugs and AF, etripamil, misuse of science, and diabetes as a cardiovascular risk factor are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript o ... Show More
21m 43s