logo
episode-header-image
Sep 2018
26m 28s

Sodium

Bbc World Service
About this episode

Sophie Scott on why sodium powers everything we do, and why it might be the key to a new generation of pain killers.

Putting sodium into water is one of the most memorable experiments from school chemistry lessons. It's this ability to react ferociously with water which is the starting point for sodium's key role in powering all of biology. Simply, without sodium we wouldn't exist. It helps provide the electricity that allows us to move, breathe, think.

Our understanding of sodium could help in the search for analgesics with few side effects for severe pain. Recent discoveries of families who feel searing pain with mild warmth, or those who feel no pain at all even in childbirth, have opened up new avenues in pain research. Their rare genetic mutations change the way sodium works in their bodies: from this new knowledge neuroscientists are developing drugs that could give rise to a much needed new generation of pain killers.

Image: Traditional glass salt cellar (Credit: Getty Images)

Up next
Jul 7
Tooth and Claw: Killer Whales
Investigating the black-and-white apex predator of the sea – the killer whale! Able to predate even great white sharks, this marine mammal is the largest member of the dolphin family. From tropical seas, to the Arctic and Antarctic, killer whales (or orcas) are found across the w ... Show More
26m 28s
Jun 30
The Life Scientific - Tim Peake
What's it like living underwater for two weeks? What's the trickiest part of training to be an astronaut? What are the most memorable sights you see from space? Several extreme questions, all of which can be answered by one man: Major Tim Peake. After a childhood packed with outd ... Show More
26m 29s
Jun 3
How does heat affect our health?
What effect will warming temperatures have on health? One place to look for answers is Bulgaria. In the summer of 2023, Bulgaria experienced numerous heatwaves, leading to the country experiencing one of the highest rates of heat mortality in Europe. But how are these numbers cal ... Show More
49m 27s
Recommended Episodes
Feb 2023
Painkillers
When it comes to shop-bought painkillers, there are rows and rows of shelves dedicated to them in supermarkets and pharmacies – ranging from own-brand tablets, to more expensive capsules and caplets, as well as branded packets that promise to work faster, and target specific pain ... Show More
26m 24s
Aug 2016
The Salt Wars
Salt is a magical substance. It reduces bitterness, enhances sweetness, boosts flavor, and preserves perishable foods. Without it, we would die: the human body can’t make sodium, but our nerves and muscles don’t work without it. It was considered rare until quite recently, so it’ ... Show More
41m 7s
Mar 2023
How We Feel Pain
How do we feel pain? What parts of the brain control our reaction to painful sensations? And how is stem cell technology revolutionising the search for better treatments for chronic pain? In this episode of How We’re Wired, join evolutionary anthropologist Dr Anna Machin as she u ... Show More
39m 44s
Jan 2023
Pain Worse at Night, Who Needs Water, Covid Nasal Spray
Today you’ll learn about the development of a potential new Covid vaccine in the form of a nasal spray, how your circadian rhythm affects how intensely you feel pain, and how the old saying that you need 8 glasses of water a day could be a myth. Pain Worse at Night “Why pain feel ... Show More
17m 48s
Mar 2023
Bacterial ‘syringes’ could inject drugs directly into human cells
00:48 Tiny syringes for drug deliveryA team of researchers have repurposed tiny syringe-like structures produced by some bacteria to deliver molecules directly into human cells. They hope that this method could be used to overcome a big challenge in modern medicine, namely ensuri ... Show More
24m 49s
Jan 2023
Amino acid slows nerve damage from diabetes, in mouse study
00:45 The role of serine in diabetic neuropathyNerve damage is a common complication of diabetes, and can even lead to limb amputation. Thus far, the only way for people to slow its onset is by managing their diet and lifestyle. Now though, research in mice shows how the amino ac ... Show More
19m 24s
Sep 2023
The Hidden Dangers Of Excessive Salt Consumption
Let’s talk about the signs you’re consuming too much salt. Top signs you’re consuming too much salt: • Edema (in the eyes, hands, feet, or lower legs) • Thirst • High blood pressure • Headache • Restlessness • Irritability • Nausea • Fatigue Top signs of sodium deficiency: • Weak ... Show More
7m 15s
Aug 2022
How to make water that's full of holes
In this episode:00:45 How adding pores helps water carry gasAlthough water is an excellent solvent, it’s limited in its ability to dissolve gasses. To overcome this a team have developed ‘porous water’ containing tiny cages that can hold large numbers of gas molecules. The team s ... Show More
30m 43s
Mar 2022
Using Salt to Optimize Mental & Physical Performance
I discuss the role of salt (sodium) in the nervous system and the key role that it plays in mental performance, physical performance and health. I explain how the brain senses salt levels in our body and how that relates to our feelings of thirst. I cover the physiology of the re ... Show More
2h 1m