NAD supplements, IVs, and patches are everywhere — and for a lot of women they do nothing or make things worse. Liz Roman and Becca Chilczenkowski explain why: an enzyme called CD38 consumes NAD and gets more active the more inflamed you are, so a big IV dose in an inflamed body can drive inflammation, anxiety, and autoimmune flares instead of energy. Inside: what NAD actually does, the three mitochondrial genes that decide if it works, NR vs NMN, and the 663-Dalton reason patches don't absorb.
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