How do scientists reason when they posit unobservables to explain their observed results? For example, how did Watson and Crick reason that DNA had a double-helix structure when they observed Franklin’s image 51, or how did Hodgkin and Huxley reason that sodium ions carried the current flowing into the membrane of a voltage-clamped giant squid axon? In Compo ... Show More
Dec 16
Mariana Ortega, "Carnalities: The Art of Living in Latinidad" (Duke UP, 2024)
How can habits of racialization be affected by art, in its reception and its creation? How can a carnal aesthetics help us understand Latinx life? What if we listen to photographs? How might they undo us? Can we be undone? In Carnalities: The Art of Living in Latinidad (Duke UP, ... Show More
1h 16m
Nov 10
Amie Thomasson, "Rethinking Metaphysics" (Oxford UP, 2025)
The word “metaphysics” conjures up thoughts of very hard questions about reality and deep, perhaps unresolvable, metaphysical mysteries. But is that the right way to think about the subject matter of metaphysics? According to Amie Thomasson, very clearly no. In her new book, Reth ... Show More
1h 3m
Oct 20
Ladelle McWhorter, "Unbecoming Persons: The Rise and Demise of the Modern Moral Self" (U Chicago Press, 2025)
How should one live? What should one do? And what do these questions have to do with being a good person? In Unbecoming Persons: The Rise and Demine of the Modern Moral Self (University of Chicago Press, 2025), Ladelle McWhorter reorients these questions through a genealogy of th ... Show More
1h 10m
Dec 2024
#97: Predictive Processing & Ultimate Well-Being - Shamil Chandaria, PhD
In this episode, Dr. Shamil Chandaria, an expert in consciousness, neuroscience, and AI, shares insights from his work on human experience and the intersection of technology and well-being. He discusses the Bayesian brain theory and the free energy principle, explaining how the b ... Show More
1h 18m
Feb 2025
523. Why We Dream, Learn, and Adapt Faster Than Any Other Species | Dr. David Eagleman
Dr. Jordan B. Peterson sits down with neuroscientist, bestselling author, and PBS presenter Dr. David Eagleman. They discuss brain plasticity, how perception works, whether free will exists (and if it’s superordinate), how willingness to engage with higher entropy indicates sophi ... Show More
1h 35m
Oct 31
Jane G. Goldberg, "Wired for Why: How We Think, Feel, and Make Meaning" (2025)
WIRED FOR WHY: How We Think, Feel and Make Meaning. (Self-Published 2025) spans eighteen chapters exploring everything from how we manage to stay alive against all odds, to why language separates us from other species, to whether death might be a metaphor. It's a journey through ... Show More
1h 3m
Jul 2025
#104: Intelligence Beyond the Brain - Nikolay Kukushkin, PhD
Can cells outside the brain learn, remember, and make decisions? In this episode, neuroscientist Dr. Nikolay Kukushkin shares groundbreaking research that shows even non-neuronal cells can recognize patterns, count, and store information in ways strikingly similar to brain cells. ... Show More
1h 12m
Jul 2024
#374 — Consciousness and the Physical World
<p>Sam Harris speaks with Christof Koch about the nature of consciousness. They discuss Christof's development as a neuroscientist, his collaboration with Francis Crick, change blindness and binocular rivalry, sleep and anesthesia, the limits of physicalism, non-locality, brains ... Show More
42m 7s