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In this episode we return to turning the open educational nursing resource for nursing pharmacology into audio, we'll start with the 1st edition antimicrobials then move on to the new second edition with the next topic. 

Summary - 3.8 Monobactams Overview and Quiz 

Chapter 3.8 of the Nursing Pharmacology guide covers monobactams, a narrow-spectrum antibiotic class primarily effective against gram-negative bacteria like Pseudomonas aeruginosa. Monobactams disrupt bacterial cell wall synthesis and are administered intravenously, intramuscularly, or via inhalation. Nurses should monitor for GI symptoms, skin sensitivities, and coagulation abnormalities. Patient education emphasizes watching for signs of superinfection or allergic reactions.

Multiple Choice Questions

1. Monobactams work primarily by:
   a) Inhibiting protein synthesis
   b) Disrupting cell wall synthesis
   c) Blocking DNA replication
   d) Preventing RNA transcription
2. Monobactams are most effective against:
   a) Gram-positive bacteria
   b) Viruses
   c) Gram-negative bacteria
   d) Fungi
3. How are monobactams commonly administered?
   a) Orally
   b) Topically
   c) Intravenously, intramuscularly, or via inhalation
   d) Subcutaneously
4. What should patients monitor for when taking monobactams?
   a) Increased appetite
   b) Hair growth
   c) Signs of superinfection
   d) Weight gain
5. Patients with allergies to which medication classes should be cautious with monobactams?
   a) Tetracyclines
   b) Penicillins, cephalosporins, or carbapenems
   c) Macrolides
   d) Antivirals

Answer Key

1. b) Disrupting cell wall synthesis
2. c) Gram-negative bacteria
3. c) Intravenously, intramuscularly, or via inhalation
4. c) Signs of superinfection
5. b) Penicillins, cephalosporins, or carbapenems