A certain class of depression drugs have been talked about in the news recently because of new info coming out about the dangers of taking them. They are called SSRIs (Selective Serotonin Re-uptake Inhibitors) — drugs that stop the brain from reabsorbing serotonin, a natural chemical in the body that helps you feel calm and...
Jul 2025
Essentials: Understanding & Conquering Depression
In this Huberman Lab Essentials episode, I explore major depression, including its underlying biology and discuss science-based approaches to alleviate symptoms and improve mood. I describe the wide-ranging symptoms of depression and explain how key neurotransmitters, hormones, s ... Show More
40m 43s
Mar 2025
The Serotonin Hypothesis: Controversies and Nuance with Awais Aftab, MD
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressant ... Show More
1h 16m
Jun 2025
Rethinking Mental Health: What The Science Actually Says About Depression, The Side Effects of Antidepressants & Finding Balance with Professor Joanna Moncrieff #563
CAUTION: If you are taking antidepressants or any other psychiatric medication, do not stop or adjust your dosage without first consulting a qualified healthcare professional. Coming off these medications without proper guidance can lead to serious withdrawal symptoms. Always see ... Show More
1h 55m
Apr 2017
TAP 204 - Robert Whitaker on The Facts And Myths About Antidepressants
<p><strong>Summary:</strong></p> <p id="yui_3_17_2_1_1492473141798_19394">This week we chat with Robert Whitaker about the myths and science behind psychiatric drugs. Robert is the author of five books. In 2010, his <em>Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, an ... Show More
1h 10m
Jul 2025
Ep 182 SSRIs Part 1: Origin
Since first hitting the shelves nearly 40 years ago, SSRIs have become one of the most commonly prescribed classes of antidepressants around the world, as well as one of the most discussed and misunderstood. This and next week, we tell the story of SSRIs in two parts. In Part 1, ... Show More
1h 2m
Nov 2023
Pharmacology of Mood Disorders Part 1
A few weeks ago, MS3 Bilal Rana hosted an episode on Mood Disorders. This is a two-part follow-up to that episode, with a packed and powerful review of the pharmacology of mood disorders – what are the drugs we use to treat mood disorders, and how do they work? In part 1, we cove ... Show More
1h 4m
Dec 2024
Exercise Compared to Medications or Therapy for Depression
Can exercise truly rival medications and therapy for treating depression? In this episode, Dr. David Puder, Dr. Nicholas Fabiano, and Dr. Brendon Stubbs dive deep into the science of physical activity as a treatment for mental health. Discover the unique antidepressant mechanisms ... Show More
1h 49m
Apr 2024
282 | Depression | Its Link to Anxiety
<p>On today's episode, join me for an in-depth discussion about the symptoms of depression, the different types of depression, how anxiety and depression go hand in hand, and some of the best ways to combat it. </p>
<p> </p>
<p>Robert Sapolsky: The Biology and Psychology of Depre ... Show More
40m 22s