In this Huberman Lab Essentials episode, I explore major depression, including its underlying biology and discuss science-based approaches to alleviate symptoms and improve mood.
I describe the wide-ranging symptoms of depression and explain how key neurotransmitters, hormones, stress, genetics and inflammation contribute to its development and persistence. ... Show More
Jul 7
How to Lose Fat & Gain Muscle With Nutrition | Alan Aragon
My guest is Alan Aragon, a renowned nutrition and fitness expert and researcher known for sharing the strongest evidence-based approaches to fat loss, muscle gain and overall health and fitness. We discuss how to optimize your protein intake, including how much to consume per mea ... Show More
2h 35m
Jun 30
The Chemistry of Food & Taste | Dr. Harold McGee
Dr. Harold McGee, PhD, is a renowned author on the topics of food chemistry and culinary science. He explains how cooking methods, types of cookware and temperature can be used to transform food and drink flavors and presents simple but powerful ways to improve nutrient availabil ... Show More
2h 13m
Jun 26
Essentials: Understanding & Treating Addiction | Dr. Anna Lembke
In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine. We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the c ... Show More
36m 32s
Apr 2024
282 | Depression | Its Link to Anxiety
On today's episode, join me for an in-depth discussion about the symptoms of depression, the different types of depression, how anxiety and depression go hand in hand, and some of the best ways to combat it.
Robert Sapolsky: The Biology and Psychology of Depression: https://ww ... Show More
40m 22s
Jun 10
Rethinking Mental Health: What The Science Actually Says About Depression, The Side Effects of Antidepressants & Finding Balance with Professor Joanna Moncrieff #563
CAUTION: If you are taking antidepressants or any other psychiatric medication, do not stop or adjust your dosage without first consulting a qualified healthcare professional. Coming off these medications without proper guidance can lead to serious withdrawal symptoms. Always see ... Show More
1h 55m
Dec 2024
Exercise Compared to Medications or Therapy for Depression
Can exercise truly rival medications and therapy for treating depression? In this episode, Dr. David Puder, Dr. Nicholas Fabiano, and Dr. Brendon Stubbs dive deep into the science of physical activity as a treatment for mental health. Discover the unique antidepressant mechanisms ... Show More
1h 49m
Mar 2025
The Serotonin Hypothesis: Controversies and Nuance with Awais Aftab, MD
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressant ... Show More
1h 16m
Dec 2024
Burnout, Functional Freeze, and Depression
Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn’t a one size fits all solution. It is agreed upon that depression is a chemical imbal ... Show More
1 h
Jul 2024
Chronic Fatigue, Functional Freeze, and Depression
Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn’t a one size fits all solution. It is agreed upon that depression is a chemical imbal ... Show More
53m 23s
May 26
Micro Habits that Fuel Depression
Join Therapy in a Nutshell’s membership and get instant access to all 10 life-changing courses, live weekly Q&As, and a supportive community for just $27/month. Learn how to manage anxiety, process trauma, regulate emotions, and build lasting resilience. Take small, powerful step ... Show More
12m 20s