In this Huberman Lab Essentials episode, I explore major depression, including its underlying biology and discuss science-based approaches to alleviate symptoms and improve mood.
I describe the wide-ranging symptoms of depression and explain how key neurotransmitters, hormones, stress, genetics and inflammation contribute to its development and persistence. ... Show More
Oct 6
How to Make Yourself Unbreakable | DJ Shipley
My guest is DJ Shipley, a retired Tier 1 operator Navy SEAL and now a top public educator on how to build mental and physical health and reach top-level performance in any endeavor. DJ’s life is one marked by extraordinary strivings, wins, setbacks and comebacks that together hav ... Show More
3h 42m
Oct 2
Essentials: How Humans Select & Keep Romantic Partners in the Short & Long Term | Dr. David Buss
In this Huberman Lab Essentials episode, my guest is Dr. David Buss, PhD, a professor of psychology at the University of Texas at Austin and a pioneer in the field of evolutionary psychology. We explore the science behind human mate selection in both short- and long-term relation ... Show More
36 m
Sep 29
Enhance Your Learning Speed & Health Using Neuroscience Based Protocols | Dr. Poppy Crum
My guest is Dr. Poppy Crum, PhD, adjunct professor at Stanford, former Chief Scientist at Dolby Laboratories and expert in neuroplasticity—our brain’s ability to change in response to experience. She explains how you can learn faster and ways to leverage your smartphone, AI and e ... Show More
2h 36m
Apr 2024
282 | Depression | Its Link to Anxiety
On today's episode, join me for an in-depth discussion about the symptoms of depression, the different types of depression, how anxiety and depression go hand in hand, and some of the best ways to combat it.
Robert Sapolsky: The Biology and Psychology of Depression: https://ww ... Show More
40m 22s
Jun 2025
Rethinking Mental Health: What The Science Actually Says About Depression, The Side Effects of Antidepressants & Finding Balance with Professor Joanna Moncrieff #563
CAUTION: If you are taking antidepressants or any other psychiatric medication, do not stop or adjust your dosage without first consulting a qualified healthcare professional. Coming off these medications without proper guidance can lead to serious withdrawal symptoms. Always see ... Show More
1h 55m
Dec 2024
Exercise Compared to Medications or Therapy for Depression
Can exercise truly rival medications and therapy for treating depression? In this episode, Dr. David Puder, Dr. Nicholas Fabiano, and Dr. Brendon Stubbs dive deep into the science of physical activity as a treatment for mental health. Discover the unique antidepressant mechanisms ... Show More
1h 49m
Mar 2025
The Serotonin Hypothesis: Controversies and Nuance with Awais Aftab, MD
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressant ... Show More
1h 16m
Dec 2024
Burnout, Functional Freeze, and Depression
Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn’t a one size fits all solution. It is agreed upon that depression is a chemical imbal ... Show More
1 h
Jul 2024
Chronic Fatigue, Functional Freeze, and Depression
Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn’t a one size fits all solution. It is agreed upon that depression is a chemical imbal ... Show More
53m 23s
May 2025
Micro Habits that Fuel Depression
Join Therapy in a Nutshell’s membership and get instant access to all 10 life-changing courses, live weekly Q&As, and a supportive community for just $27/month. Learn how to manage anxiety, process trauma, regulate emotions, and build lasting resilience. Take small, powerful step ... Show More
12m 20s