In this Huberman Lab Essentials episode, I explore major depression, including its underlying biology and discuss science-based approaches to alleviate symptoms and improve mood.
I describe the wide-ranging symptoms of depression and explain how key neurotransmitters, hormones, stress, genetics and inflammation contribute to its development and persistence. ... Show More
Today
Science-Based Meditation Tools to Improve Your Brain & Health | Dr. Richard Davidson
Dr. Richard Davidson, PhD, is a professor of psychology and psychiatry at the University of Wisconsin–Madison and a pioneer in the scientific study of meditation. We discuss how meditation changes your brain and body, how just 5 minutes daily can improve focus, stress resilience ... Show More
2h 43m
Mar 12
Essentials: Benefits of Sauna & Deliberate Heat Exposure
In this Huberman Lab Essentials episode, I discuss the mechanisms through which deliberate heat exposure enhances both physical and mental health. I outline specific protocols for deliberate heat exposure, including recommended temperature ranges, frequency, timing, duration and ... Show More
43m 48s
Mar 9
Avoiding, Treating & Curing Cancer With the Immune System | Dr. Alex Marson
Dr. Alex Marson, MD, PhD, is a Senior Investigator at the Gladstone Institutes and a professor of medicine at the University of California, San Francisco. We discuss the biology of the immune system and cancer, and everyday choices that can increase or decrease your cancer risk, ... Show More
2h 27m
Apr 2024
282 | Depression | Its Link to Anxiety
<p>On today's episode, join me for an in-depth discussion about the symptoms of depression, the different types of depression, how anxiety and depression go hand in hand, and some of the best ways to combat it. </p>
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<p>Robert Sapolsky: The Biology and Psychology of Depre ... Show More
40m 22s
Jun 2025
Rethinking Mental Health: What The Science Actually Says About Depression, The Side Effects of Antidepressants & Finding Balance with Professor Joanna Moncrieff #563
CAUTION: If you are taking antidepressants or any other psychiatric medication, do not stop or adjust your dosage without first consulting a qualified healthcare professional. Coming off these medications without proper guidance can lead to serious withdrawal symptoms. Always see ... Show More
1h 55m
Dec 2024
Exercise Compared to Medications or Therapy for Depression
Can exercise truly rival medications and therapy for treating depression? In this episode, Dr. David Puder, Dr. Nicholas Fabiano, and Dr. Brendon Stubbs dive deep into the science of physical activity as a treatment for mental health. Discover the unique antidepressant mechanisms ... Show More
1h 49m
Mar 2025
The Serotonin Hypothesis: Controversies and Nuance with Awais Aftab, MD
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressant ... Show More
1h 16m
Mar 2025
Is Exercise the Miracle Drug We’ve Been Waiting For? The Number One Way to Strengthen Your Mind and Fight Depression with Dr. Nicholas Fabiano
This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15. When we think about treating depression, we rarely consider exercise. Yet emerging research shows it can be a powerful tool for managing mild to moderate depression, and it works well alongside other therapi ... Show More
1h 14m
Dec 2024
Burnout, Functional Freeze, and Depression
<p dir="ltr">Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn't a one size fits all solution.<br /> <br /> It is agreed upon that depr ... Show More
1 h
Jul 2024
Chronic Fatigue, Functional Freeze, and Depression
<p dir="ltr">Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn't a one size fits all solution.<br /> <br /> It is agreed upon that depr ... Show More
53m 23s