In this Huberman Lab Essentials episode, I explore major depression, including its underlying biology and discuss science-based approaches to alleviate symptoms and improve mood.
I describe the wide-ranging symptoms of depression and explain how key neurotransmitters, hormones, stress, genetics and inflammation contribute to its development and persistence. ... Show More
Nov 20
Essentials: Science of Building Strong Social Bonds with Family, Friends & Romantic Partners
In this Huberman Lab Essentials episode, I discuss the science of social connection and how we form meaningful bonds with others.
I explore the neural basis for "social homeostasis"—our drive for a certain amount of social interaction—which explains why we feel lonely, seek conn ... Show More
36m 33s
Nov 17
How to Speak Clearly & With Confidence | Matt Abrahams
My guest is Matt Abrahams, lecturer at Stanford Graduate School of Business and a world expert in communication and public speaking. He explains how to speak with clarity and confidence and how to be more authentic in your communication in all settings: public, work, relationship ... Show More
2h 26m
Nov 13
Essentials: Breathing for Mental & Physical Health & Performance | Dr. Jack Feldman
In this Huberman Lab Essentials episode, my guest is Dr. Jack Feldman, PhD, a Distinguished Professor of Neurobiology at the University of California, Los Angeles, and a leading expert in the science of breathing. We explain the mechanics of breathing and the neural circuits that ... Show More
49m 45s
Apr 2024
282 | Depression | Its Link to Anxiety
<p>On today's episode, join me for an in-depth discussion about the symptoms of depression, the different types of depression, how anxiety and depression go hand in hand, and some of the best ways to combat it. </p>
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<p>Robert Sapolsky: The Biology and Psychology of Depre ... Show More
40m 22s
Jun 2025
Rethinking Mental Health: What The Science Actually Says About Depression, The Side Effects of Antidepressants & Finding Balance with Professor Joanna Moncrieff #563
CAUTION: If you are taking antidepressants or any other psychiatric medication, do not stop or adjust your dosage without first consulting a qualified healthcare professional. Coming off these medications without proper guidance can lead to serious withdrawal symptoms. Always see ... Show More
1h 55m
Dec 2024
Exercise Compared to Medications or Therapy for Depression
Can exercise truly rival medications and therapy for treating depression? In this episode, Dr. David Puder, Dr. Nicholas Fabiano, and Dr. Brendon Stubbs dive deep into the science of physical activity as a treatment for mental health. Discover the unique antidepressant mechanisms ... Show More
1h 49m
Mar 2025
The Serotonin Hypothesis: Controversies and Nuance with Awais Aftab, MD
Is depression really caused by low serotonin? Dr. Awais Aftab joins Dr. David Puder to explore the serotonin hypothesis, antidepressant efficacy, and the controversies surrounding SSRIs. They dive into the history of the serotonin deficiency theory, key research on antidepressant ... Show More
1h 16m
Mar 2025
Is Exercise the Miracle Drug We’ve Been Waiting For? The Number One Way to Strengthen Your Mind and Fight Depression with Dr. Nicholas Fabiano
This episode is brought to you by BiOptimizers, Cozy Earth, and Fatty15. When we think about treating depression, we rarely consider exercise. Yet emerging research shows it can be a powerful tool for managing mild to moderate depression, and it works well alongside other therapi ... Show More
1h 14m
Dec 2024
Burnout, Functional Freeze, and Depression
<p dir="ltr">Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn't a one size fits all solution.<br /> <br /> It is agreed upon that depr ... Show More
1 h
Jul 2024
Chronic Fatigue, Functional Freeze, and Depression
<p dir="ltr">Depression is one of the most researched mood disorders, but if we look a bit deeper into how depression is able to develop, it is more nuanced than we think. This means, treating depression isn't a one size fits all solution.<br /> <br /> It is agreed upon that depr ... Show More
53m 23s