logo
episode-header-image
Dec 2024
32m 16s

#166 Stress Ulcer Prophylaxis in the ICU...

CORE IM TEAM
About this episode

What’s the evidence been for the use of PPIs in mechanically ventilated patients? What do more recent studies reveal about PPIs and possible harmful side effects of aspiration pneumonia and C. difficile colitis? To find out, tune into the second season of Beyond Journal Club, a series brought to you by Core IM in collaboration with NEJM Group.

SponsorFreed is an AI scribe that listens and writes your note in < 30 seconds. Freed learns your style over time and is HIPAA compliant! 

Use the code CORE50 to get 50% off your first month with Freed

Subscribe to Core IM’s YouTube Channel for more behind the scenes, whiteboard animations and more!

Timestamps:

(02:13) | Define the problem / Clinically important bleeding Outcome/Risk benefit /Risk factors]

(05:58) | Hx and H2 antagonists

(10:42) | SUP-ICU

(15:12) | PEPTIC

(19:30) | REVISE trial

(27:28) | Deprescribing

(29:06) | Outstanding questions

Transcript and Show Notes

Tags: CoreIM, InternalMedicine, CriticalCare, Proton Pump Inhibitors, GIbleeding, ICU, ICU bleeding, Clinical Trials, Evidence Based Medicine, Patient Centered Outcomes, Deprescribing



Find the best disability insurance for you: https://www.patternlife.com/disability-insurance?campid=497840

Our Sponsors:
* Check out Branch Basics: https://branchbasics.com/COREIM and use the code CoreIM for 15%
* Check out FIGS and use my code FIGSRX for a great deal: https://wearfigs.com
* Check out Uncommon Goods for 15% off: https://uncommongoods.com/COREIM
* Check out Washington Red Raspberries: https://redrazz.org


Advertising Inquiries: https://redcircle.com/brands

Privacy & Opt-Out: https://redcircle.com/privacy
Up next
Nov 19
#193 Venous Congestion & VEXUS Interview with Dr. Ross Prager
<p>Why is venous congestion not the same as volume overload? How can looking at IVC as well as doppler on the hepatic vein, portal vein, and/or intrarenal vein help? Can venous congestion explain someone&#39;s delirium? Or be at play in septic shock? What are the limitations of t ... Show More
34m 44s
Nov 5
#192 Debate on First-Line Medications for Diabetes
<p>SGLT-2i vs. GLP-1? vs Metformin? How do you balance the cost and coverage of first-line options like metformin, SGLT-2, and GLP-1s? How do you choose between SGLT-2 and GLP-1s for comorbidities like CAD or CKD? And how do you weigh their side effects and practical use?</p><p>< ... Show More
36m 50s
Oct 22
#191 Hepatorenal Syndrome Part 2 on Management: 5 Pearls Segment
<p>What really works when treating HRS? Vasoconstrictors like terlipressin vs. norepinephrine vs. midodrine: how do we decide which to use? Do you give albumin? When do you give Lasix or another diuretic? When is the better choice transplant, dialysis, or even palliative care?</p ... Show More
31m 35s
Recommended Episodes
Jan 2025
409. Journal Club: The ARREST-AF Trial with Drs. Prashanthan Sanders and Mehak Dhande
Join CardioNerds EP Council Chair Dr. Naima Maqsood and Episode Lead Dr. Jeanne De Lavallaz as they discuss the results of the ARREST-AF Trial with expert faculty Dr. Prashanthan Sanders and Dr. Mehak Dhande. Audio editing by CardioNerds intern Bhavya Shah. The ARREST-AF trial en ... Show More
36m 4s
Oct 2024
#458 HFrEF: Heart Failure with Reduced Ejection Fraction
Kittleson Rules Outpatient Heart Failure Volume 1 Provide superb outpatient care for your patients with HFrEF. Identify underlying causes of heart failure and titrate medications with ease. Dr Michelle Kittleson @MKittlesonMD (Cedars Sinai) breaks down the nuances of treating thi ... Show More
1h 4m
Dec 2023
The Impact of Microcirculation Assessment in ICU Shock Patients: Insights from the DAMIS Trial
In this episode, we delve into the groundbreaking DAMIS trial, exploring the impact of sublingual microcirculation assessment on treatment decisions for ICU patients with shock. We discuss the methodology, findings, and implications of this extensive multicenter study, offering i ... Show More
5m 15s
Jun 2024
Trial of the Week: PROWESS-SHOCK
Trial of the Week: PROWESS-SHOCKSpecial Guest: Paul Szumita, PharmD, FCCM, FASHP, BCCCP, BCPS @paulszumita 03:30 – Background studies/Setting the scene30:25 – PROWESS-SHOCK discussion/Where are we now Paul Szumita joins to highlight a June Trial of the Week “Drotrecogin alfa (act ... Show More
1 h
Oct 2020
64. Case Report: RV Infarction Treated with RVAD Support – Houston Methodist
CardioNerds (Amit Goyal & Daniel Ambinder) join Houston Methodist cardiology fellows (Isaac Tea, Stephanie Fuentes, Peter Rothstein) for a trip to Hermann Park! They discuss a challenging case of right ventricular (RV) infarction leading to acute RV failure treated with right ven ... Show More
1h 16m
Jun 2025
Dapagliflozin in Patients Undergoing Transcatheter Aortic Valve Implantation
The DapaTAVI trial, conducted across 39 centers in Spain, is the first study to evaluate the use of sodium-glucose co-transporter-2 (SGLT-2) inhibitors, specifically dapagliflozin, in patients with heart failure undergoing transcatheter aortic valve implantation (TAVI). The trial ... Show More
9m 4s
Sep 12
Sep 12 2025 This Week in Cardiology
More from ESC including: Valvular HD guidelines, a new drug class for HTN, myosin inhibition in HCM, vericiguat, and digoxin are the topic discussed by John Mandrola, MD. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit ... Show More
31m 5s
Oct 2024
393. SGLT Inhibitors: Clinical Implementation of SGLT Inhibitors with Dr. Alison Bailey
CardioNerds Drs. Jason Feinman, Gurleen Kaur, and Rick Ferraro discuss the implementation of SGLT inhibitors in clinical practice with Dr. Alison Bailey. Notes were drafted by Dr. Jason Feinman. In this episode, we discuss the implementation of SGLTi in clinical practice scena ... Show More
19m 21s
Feb 2025
411. Journal Club: The VANISH2 Trial with Dr. Jeff Healey and Dr. Roderick Tung
Join CardioNerds EP Council Chair Dr. Naima Maqsood and Episode Lead Dr. Jeanne De Lavallaz as they discuss the results of the VANISH2 Trial with expert faculty Dr. Jeff Healey and Dr. Roderick Tung. Audio editing by CardioNerds academy intern, Grace Qiu. The VANISH2 trial enroll ... Show More
30m 5s
Jan 2025
Review of the Primary Angioplasty in Myocardial Infarction Study Group trial
N Engl J Med 1993;328:673-679Background: Previous trials established that thrombolysis improves mortality in patients with acute myocardial infarction, as seen in the GISSI-1 and ISIS-2 trials. However, thrombolysis has limitations, including an increased risk of bleeding and the ... Show More
12m 26s