logo
episode-header-image
Dec 2023
5m 15s

The Impact of Microcirculation Assessmen...

Eddy Joe Gutierrez, MD
About this episode

In this episode, we delve into the groundbreaking DAMIS trial, exploring the impact of sublingual microcirculation assessment on treatment decisions for ICU patients with shock. We discuss the methodology, findings, and implications of this extensive multicenter study, offering insights into how real-time microcirculatory data influences clinical outcomes in critical care. Join us for an in-depth analysis and expert opinions on this pivotal topic in intensive care medicine.

Show Notes: https://eddyjoemd.com/damis-trial-microcirculation/

The Vasopressor & Inotrope Handbook: ⁠Amazon Affiliate Link⁠ (I will earn an extra small commission) and ⁠Signed Copies⁠.

Citation: Bruno RR, Wollborn J, Fengler K, Flick M, Wunder C, Allgäuer S, Thiele H, Schemmelmann M, Hornemann J, Moecke HME, Demirtas F, Palici L, Franz M, Saugel B, Kattan E, De Backer D, Bakker J, Hernandez G, Kelm M, Jung C. Direct assessment of microcirculation in shock: a randomized-controlled multicenter study. Intensive Care Med. 2023 Jun;49(6):645-655. doi: 10.1007/s00134-023-07098-5. Epub 2023 Jun 6. Erratum in: Intensive Care Med. 2023 Oct;49(10):1279. PMID: 37278760; PMCID: PMC10242221.

This Podcast was edited using Descript: ⁠⁠⁠⁠⁠https://www.descript.com?lmref=BGOxjQ⁠⁠⁠⁠

Up next
Jul 3
Sodium Bicarbonate for ICU Acidosis: New Evidence Supporting a Controversial Therapy
In this episode of the Saving Lives Podcast, we break down a 2025 study from Intensive Care Medicine that emulates a target trial on the use of sodium bicarbonate in ICU patients with metabolic acidosis. With over 6,000 patients across 12 Australian ICUs, the study reveals a smal ... Show More
6m 7s
Jul 1
Predicting Mortality in a Pulmonary Embolism: What the Data Really Tells Us
In this episode of the Saving Lives Podcast, we review a comprehensive 2025 meta-analysis on mortality risk factors in pulmonary embolism. Learn which clinical signs, biomarkers, and imaging findings most strongly predict outcomes — and how they can guide triage and therapy decis ... Show More
6m 31s
Jun 26
Hyponatremia Correction: Is Going Too Slow Riskier Than You Think?
In this episode of the Saving Lives Podcast, we review a 2025 NEJM-Evidence study analyzing over 21,000 cases of severe hyponatremia to determine the safest and most effective correction rates. Learn why moderate correction (8–10 mmol/L/day) may actually reduce mortality, and how ... Show More
5m 52s
Recommended Episodes
Jul 2023
Prof. John Myburgh talks Fluids, Catecholamines, South Africa and a little bit of Research.
In this episode, we have the honor of speaking with Professor John Myburgh, a former South African physician and researcher who has dedicated his life to improving the field of critical care medicine. Professor Myburgh has made significant contributions to the field of fluid resu ... Show More
33m 24s
Sep 2024
Sep 20 2024 This Week in Cardiology
Listener feedback, K levels post cardiac surgery, cardiac device safety, disparities in preventive care, stopping trials early, and a SHAM-PVI update are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial ... Show More
22m 39s
Dec 2024
#166 Stress Ulcer Prophylaxis in the ICU and REVISE Trial: Beyond Journal Club with NEJM Group
What’s the evidence been for the use of PPIs in mechanically ventilated patients? What do more recent studies reveal about PPIs and possible harmful side effects of aspiration pneumonia and C. difficile colitis? To find out, tune into the second season of Beyond Journal Club, a s ... Show More
32m 16s
Jan 2025
Prehabilitation before surgery, alcohol's impact on clinical care, and life after a cardiac arrest
Exercise and a better diet, prior to surgery, can improve outcomes. Daniel McIsaac, a professor of anaesthesiology from the University of Ottowa and lead author of that research, joins us to talk about getting those results into practice. Julia Sinclair, professor of addiction ps ... Show More
40m 40s
Dec 2024
Top Takeaways from 2024: Interventional Cardiology with Deepak L. Bhatt, MD, MPH, MBA, FACC
In this interview, Deepak L Bhatt, MD, MPH, MBA, FACC, and Alison L. Bailey, MD FACC, discuss the Top Interventional Takeaways from 2024. Dr. Bhatt discusses the CLEAR SYNERGY, DanGer Shock, EARLY TAVR trials and more.   Jolly SS, d’Entremont MA, Lee SF, et al., for the CLEAR Inv ... Show More
16m 1s
Mar 2023
"The Problem with Clinical Trials" with Jonathan Shedler, PhD
Jonathan Shedler, Phd is a clinical professor of psychiatry at the University of California, San Francisco (UCSF) and faculty member at the San Francisco Center for Psychoanalysis. He is author of numerous scientific and scholarly articles, and his article The Efficacy of Psychod ... Show More
1h 5m
Aug 2024
Aug 02 2024 This Week in Cardiology
Two downsides of PFA including autonomic tone and hemolysis, a bad surrogate in AF care, and controversies in defining cardiac risk are the topics John Mandrola, MD, covers in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial trans ... Show More
28m 50s
Jan 2025
JVS CIT Editorials and Abstracts - Dec 2024/Jan 2025
In this episode, we spotlight editorials and abstracts from the Journal of Vascular Surgery Cases, Innovations, and Techniques (JVS-CIT). Editorials and Abstracts are read by members of the SVS Social Media Ambassadors. Guests: Dr. Gregory Magee, MD (@gregamagee) The past, presen ... Show More
56m 3s
Feb 2025
PTJ Author Interview: Randomized Clinical Trials and Real-World Practice
In this episode of the PTJ Podcast, Editor-in-Chief Steven George, PT, PhD, FAPTA, talks with Alexander Garbin, PT, DPT, PhD, and Jennifer Stevens-Lapsley, PT, PhD, FAPTA, about their recently published companion papers, which evaluated the effectiveness of a progressive multicom ... Show More
24m 12s
Feb 2025
LifeBTK Trial: Drug-Eluting Resorbable Scaffold versus Angioplasty for Infrapopliteal Artery Disease
In this episode of Audible Bleeding, Jamila, Anh, and Naveed discuss the LifeBTK Trial with Principal Investigator Dr. Brian DeRubertis, where we discuss the new Abbott Esprit everolimus-eluting resorbable scaffold for the below-knee popliteal space. Guest: Dr. DeRubertis, is the ... Show More
47m 12s