In this episode, we’re joined by Noam Baumatz, CEO and Co-Founder of Noga Therapeutics, a company dedicated to developing gene therapies for rare and severe diseases through engineering macrophages. Motivated by his highly personal experience of rare disease, Noam founded Noga to develop the type of gene therapies his daughter was unable to access. He and Pa ... Show More
Aug 21
EP 201: The gene therapy playbook: Successes, setbacks, and the path forward with Richard Wilson of Astellas
This week on The Genetics Podcast, Patrick is joined by Richard Wilson, Senior Vice President, Primary Focus Lead of Genetic Regulation at Astellas. They discuss where the gene therapy field stands today, diving into successes, persistent barriers, regulatory considerations, manu ... Show More
47m 28s
Aug 14
EP 200: From predictions to breakthroughs in genetics and biotech
This week on The Genetics Podcast, we celebrate our 200th episode with a look back at some of the earliest episodes, particularly ones that foresaw major trends or went on to spark real-world impact. These include Eric Topol’s early predictions about AI in healthcare, Laurence Re ... Show More
34m 40s
Aug 7
EP 199: Functional genomics at scale: Using in vivo perturbations to study genetic risk variants in the brain with Xin Jin of Scripps Research Institute
This week on The Genetics Podcast, Patrick is joined by Xin Jin, Associate Professor in the Department of Neuroscience at The Scripps Research Institute. They discuss how in vivo Perturb-seq enables scalable and high-resolution modeling of neurogenetic disorders like autism, how ... Show More
36m 31s
Oct 2023
How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a reco ... Show More
1h 50m
Jul 2024
Audio long read: Hope, despair and CRISPR — the race to save one woman’s life
In India, a group of researchers raced to develop a CRISPR-based genome editing therapy to save the life of a young woman with a rare neurodegenerative disease. Despite a valiant effort, the pace of research was ultimately too slow to save her life. While many are convinced that ... Show More
23m 4s
May 16
How to Cure What Ails You
Now that we have the ability to see inside the brain without opening anyone's skull, we'll be able to map and define brain activity and peg it to behavior and feelings. Right? Well, maybe not, or maybe not just yet. It seems the workings of our brains are rather too complex and d ... Show More
25m 1s
May 2024
Mini Episode: Enhance Stem Cell Activation Through Hyperbarics - Dr. Allen Meglin : 1163
We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Dr. Allen Meglin and Oxy Health are at the forefront of hyperbaric medicine, a field revolutionizing the way we enhance healing and cellular health. Hyperbaric oxygen ... Show More
13m 31s
Dec 2024
Episode 107: Immunogenetics Unlocked: The Gene Discovery Journey
In this episode with Dr. Cybel Mehawej of the Lebanese American University Human Genetics Department, and co-hosted with MohammadAli Jardaly, we explore the gene discovery process at the intersection of genetics and immunology. Dr. Mehawej, along with the team at the LAU Medical ... Show More
25m 8s
May 2022
S2 002: Rudy Benfredj at Mendelian ➡️ Rare diseases, genetics, AI. 🧬🤖🏥
A computer scientist fascinated by the genetic code and its application to rare disease, Rudy Benfredj moved into healthtech and cofounded Mendelian. Mendelscan, their core technology helps identify patients at risk of developing a rare disease early. We touch on the patient’s di ... Show More
31m 23s