In this episode, we’re joined by Noam Baumatz, CEO and Co-Founder of Noga Therapeutics, a company dedicated to developing gene therapies for rare and severe diseases through engineering macrophages. Motivated by his highly personal experience of rare disease, Noam founded Noga to develop the type of gene therapies his daughter was unable to access. He and Pa ... Show More
Yesterday
EP 208: Gene therapy at a crossroads: Successes, concerns, and the path forward
Summary: This week on The Genetics Podcast, Patrick Short takes a solo deep dive into the current state of gene therapy ahead of next week’s live recording at ASHG. He explores the promise and limitations of adeno-associated virus (AAV) delivery, examples of gene therapies for ne ... Show More
42m 58s
Oct 2
EP 207: Decoding Parkinson’s genetics on a global scale with Andy Singleton and Sonya Dumanis of GP2 and ASAP
Summary: This week on The Genetics Podcast, Patrick is joined by Andy Singleton, Program Lead of the Global Parkinson’s Genetics Program (GP2), and Sonya Dumanis, COO of the Coalition for Aligning Science. They discuss the creation of GP2, how the initiative is closing representa ... Show More
43m 51s
Sep 25
EP 206: From caregiving to catalyzing FTD research with Wanda Smith of CureGRN
This week on The Genetics Podcast, Patrick is joined by Wanda Smith, founder of CureGRN. They discuss Wanda’s journey from caring for her mother to driving FTD research, the discovery of progranulin and development of new therapies, the diagnostic odyssey and need for earlier gen ... Show More
38m 34s
Oct 2023
How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a reco ... Show More
1h 50m
Jul 2024
Audio long read: Hope, despair and CRISPR — the race to save one woman’s life
In India, a group of researchers raced to develop a CRISPR-based genome editing therapy to save the life of a young woman with a rare neurodegenerative disease. Despite a valiant effort, the pace of research was ultimately too slow to save her life. While many are convinced that ... Show More
23m 4s
May 2025
How to Cure What Ails You
Now that we have the ability to see inside the brain without opening anyone's skull, we'll be able to map and define brain activity and peg it to behavior and feelings. Right? Well, maybe not, or maybe not just yet. It seems the workings of our brains are rather too complex and d ... Show More
25m 1s
Aug 22
The Medical Matchmaking Machine
As he finished his medical school exam, David Fajgenbaum felt off. He walked down to the ER and checked himself in. Soon he was in the ICU with multiple organ failure. The only drug for his condition didn’t work. He had months to live, if that. If he was going to survive, he was ... Show More
1h 1m
May 2024
Mini Episode: Enhance Stem Cell Activation Through Hyperbarics - Dr. Allen Meglin : 1163
We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on The Human Upgrade! Dr. Allen Meglin and Oxy Health are at the forefront of hyperbaric medicine, a field revolutionizing the way we enhance healing and cellular health. Hyperbaric oxygen ... Show More
13m 31s
Dec 2024
Episode 107: Immunogenetics Unlocked: The Gene Discovery Journey
In this episode with Dr. Cybel Mehawej of the Lebanese American University Human Genetics Department, and co-hosted with MohammadAli Jardaly, we explore the gene discovery process at the intersection of genetics and immunology. Dr. Mehawej, along with the team at the LAU Medical ... Show More
25m 8s
Jan 2025
Unlocking green hydrogen, and oxygen deprivation as medicine
First up this week, although long touted as a green fuel, the traditional approach to hydrogen production is not very sustainable. Staff writer Robert F. Service joins producer Meagan Cantwell to discuss how researchers are aiming to improve electrolyzers—devices that split water ... Show More
34m 12s
Feb 2025
Steven Lesk, "Footprints of Schizophrenia: The Evolutionary Roots of Mental Illness" (Prometheus, 2023)
Of all the mental illnesses, schizophrenia eludes us the most. No matter the strides scientists have made in neurological research nor doctors have made in psychiatric treatment, schizophrenia remains misunderstood, almost complacently mythologized. Without a reason for the illne ... Show More
1h 5m