In this episode, we’re joined by Noam Baumatz, CEO and Co-Founder of Noga Therapeutics, a company dedicated to developing gene therapies for rare and severe diseases through engineering macrophages. Motivated by his highly personal experience of rare disease, Noam founded Noga to develop the type of gene therapies his daughter was unable to access. He and Pa ... Show More
Nov 20
EP 214: Innovating large-scale and sustainable genomics with Slavé Petrovski of AstraZeneca
<p><strong>Summary: </strong></p><p>This week on The Genetics Podcast, Patrick is joined by Slavé Petrovski, Vice President of the Center for Genomics Research at AstraZeneca. They discuss how AstraZeneca is scaling population genomics through massive biobank collaborations, deve ... Show More
51m 19s
Nov 13
EP 213: Inside the science of hearing loss and gene therapy for deafness with Ellen Reisinger of the University of Tübingen
This week on The Genetics Podcast, Patrick is joined by Dr. Ellen Reisinger, Professor and group leader at the University of Tübingen. They discuss her journey into hearing loss research, why otoferlin has become a leading target for gene therapy, and the emerging science shaping ... Show More
35m 29s
Nov 6
EP 212: A hub-and-spoke model for accelerating rare disease drug development with Ananth Sridhar and Sun-Gou Ji of BridgeBio
Summary: This week on The Genetics Podcast, Patrick is joined by BridgeBio’s Ananth Sridhar, Chief Operating Officer of Cardiorenal Programs, and Sun-Gou Ji, Vice President of Computational Genomics. They discuss the hub-and-spoke model for de-risking and accelerating rare diseas ... Show More
46m 5s
Oct 2023
How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
<p>In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. </p><p>He ... Show More
1h 50m
Jul 2024
Audio long read: Hope, despair and CRISPR — the race to save one woman’s life
In India, a group of researchers raced to develop a CRISPR-based genome editing therapy to save the life of a young woman with a rare neurodegenerative disease. Despite a valiant effort, the pace of research was ultimately too slow to save her life. While many are convinced that ... Show More
23m 4s
May 2025
How to Cure What Ails You
<p>Now that we have the ability to see inside the brain without opening anyone's skull, we'll be able to map and define brain activity and peg it to behavior and feelings. Right? Well, maybe not, or maybe not just yet. It seems the workings of our brains are rather too complex an ... Show More
25m 1s
Aug 22
The Medical Matchmaking Machine
<p>As he finished his medical school exam, David Fajgenbaum felt off. He walked down to the ER and checked himself in. Soon he was in the ICU with multiple organ failure. The only drug for his condition didn’t work. He had months to live, if that. If he was going to survive, ... Show More
1h 1m
May 2024
Mini Episode: Enhance Stem Cell Activation Through Hyperbarics - Dr. Allen Meglin : 1163
<p>We're previewing the 10th annual Biohacking Conference in Dallas, Texas, (May 30 - June 1) on <em>The Human Upgrade</em>! </p><p>Dr. Allen Meglin and Oxy Health are at the forefront of hyperbaric medicine, a field revolutionizing the way we enhance healing and cellular he ... Show More
13m 31s
Dec 2024
Episode 107: Immunogenetics Unlocked: The Gene Discovery Journey
<p>In this episode with Dr. Cybel Mehawej of the Lebanese American University Human Genetics Department, and co-hosted with MohammadAli Jardaly, we explore the gene discovery process at the intersection of genetics and immunology. Dr. Mehawej, along with the team at the LAU Medic ... Show More
25m 8s
Jan 2025
Unlocking green hydrogen, and oxygen deprivation as medicine
First up this week, although long touted as a green fuel, the traditional approach to hydrogen production is not very sustainable. Staff writer Robert F. Service joins producer Meagan Cantwell to discuss how researchers are aiming to improve electrolyzers—devices that split water ... Show More
33m 12s
Feb 2025
Steven Lesk, "Footprints of Schizophrenia: The Evolutionary Roots of Mental Illness" (Prometheus, 2023)
Of all the mental illnesses, schizophrenia eludes us the most. No matter the strides scientists have made in neurological research nor doctors have made in psychiatric treatment, schizophrenia remains misunderstood, almost complacently mythologized. Without a reason for the illne ... Show More
1h 2m