logo
episode-header-image
Aug 22
1h 1m

The Medical Matchmaking Machine

Wnyc Studios
About this episode

As he finished his medical school exam, David Fajgenbaum felt off.  He walked down to the ER and checked himself in.  Soon he was in the ICU with multiple organ failure.  The only drug for his condition didn’t work. He had months to live, if that.  If he was going to survive, he was going to have to find his own cure. Miraculously, he pulled it off in the nick of time. From that ordeal, he realized that our system of discovering and approving drugs is far from perfect, and that he might be able to use AI to find dozens, hundreds, even thousands of cures, hidden in plain sight, for as-yet untreatable diseases. 

EPISODE CREDITS:
Reported by - Latif Nasser
Produced by - Maria Paz Gutiérrez
with mixing help from - Jeremy S. Bloom
Fact-checking by - Natalie A. Middleton

VISIT:
Everycure.org (https://www.everycure.org)

EPISODE CITATIONS:
Books -
Blair Bigham -  Death Interrupted: How Modern Medicine is Complicating the Way We Die

David Fajgenbaum - Chasing My Cure, (https://davidfajgenbaum.com/)

Radiolab | Lateral Cuts:
Check out Death Interrupted (https://radiolab.org/podcast/death-interrupted), a conversation with Blair Bigham about a worldview shifting change of heart.

The Dirty Drug and the Ice Cream Tub (https://radiolab.org/podcast/dirty-drug-and-ice-cream-tub) to hear the crazy story about how Rapamycin was discovered.

Signup for our newsletter!! It includes short essays, recommendations, and details about other ways to interact with the show. Sign up (https://radiolab.org/newsletter)!

Radiolab is supported by listeners like you. Support Radiolab by becoming a member of The Lab (https://members.radiolab.org/) today.

Follow our show on Instagram, Twitter and Facebook @radiolab, and share your thoughts with us by emailing radiolab@wnyc.org.

Leadership support for Radiolab’s science programming is provided by the Simons Foundation and the John Templeton Foundation. Foundational support for Radiolab was provided by the Alfred P. Sloan Foundation.

Up next
Aug 15
Weighing Good Intentions
In an episode first released in 2010, then-producer Lulu Miller drives to Michigan to track down the endangered Kirtland’s warbler. Efforts to protect the bird have lead to the killing of cowbirds (a species that commandeers warbler nests), and a prescribed burn aimed at creating ... Show More
25m 29s
Aug 8
The Menopause Mystery
Until recently, scientists assumed humans were the only species in which females went through menopause, and lived a substantial part of their lives after they were no longer able to reproduce. And they had no idea why that happens, and why evolution wouldn’t push females to keep ... Show More
38m 58s
Aug 1
Galaxy Quenching
This week: the story of astrophysicist Charity Woodrum. Charity is an extragalactic astronomer who studies the life and death of galaxies, why some galaxies burn bright and others dim and sputter out. And in the midst of an unthinkable grief in her personal life, she discovers so ... Show More
40m 8s
Recommended Episodes
Jun 2024
An Alibi for Ecocide
An apparent "success story" of Amazonian forest conservation motivates a 6-years investigation of the land sparing hypothesis. Dr. Gregory Thaler's new book, Saving a Rainforest and Losing the World, reveals a tragic belief that agricultural intensification will solve our problem ... Show More
1h 13m
Dec 2024
Meet Leaders Of 3 Local Conservation Projects | Preserving ‘Space Junk’ Left On Mars
What makes three very different conservation projects so successful? These experts say it’s getting the community involved. And, archaeologists make a case for tracking and preserving artifacts left on Mars to chronicle humans’ first attempts at interplanetary exploration.Meet 3 ... Show More
18m 21s
Jun 30
Talking to the Host of Drilled about the Legal Battles around Standing Rock
Protests around the construction of the now complete Dakota Access Pipeline brought national attention to Energy Transfer, the company that built and owns the pipeline and funded private security against the protestors. Energy Transfer sued the nonprofit Greenpeace for hundreds o ... Show More
13m 6s
Jun 2015
Episode 03: Jane Goodall
Dr. Jane Goodall is a legend. She is a science hero, a trailblazing researcher who inspires people around the world. In this episode, Jane Goodall shares part of the story of how she went from working as a secretary to becoming the world's leading expert on chimpanzee behavior. I ... Show More
24m 25s
Jan 2023
Top Human Origins Discoveries of 2022
2022 was another exciting year in human origins research! New fossil discoveries and ancient DNA research expanded our understanding of the past. We learned something surprising about the evolution of human speech, and new methodologies and showed promising potential to improve t ... Show More
35m 5s
May 2024
The Department of Living Animals
The Smithsonian National Zoological Park in Washington, DC is sometimes called “the people’s zoo.” That’s because it’s the only zoo in the country to be created by an act of US Congress, and admission is free.But why did our federal government create a national zoo in the first p ... Show More
27m 52s
Oct 2023
Kendra Coulter, "Defending Animals: Finding Hope on the Front Lines of Animal Protection" (MIT Press, 2023)
Beloved dogs and cats. Magnificent horses and mountain gorillas. Curious chickens. What do we actually do to protect animals from harm—and is it enough? This engaging book provides a unique and eye-opening exploration of the world of animal protection as people defend diverse ani ... Show More
59m 14s
Jan 2019
Episode 34: From the Archive - Margaret Mead
In this never-before-released archival lecture from 1974, anthropologist Margaret Mead discusses the lives of women from prehistoric through modern times. Show Notes The Leakey Foundation is 50 years old this year, and we’re celebrating this milestone by sharing rare, previously ... Show More
51m 41s
Aug 2023
Hawai’i Wildfires, Blue-Fin Tuna Science, Maine’s New Lithium Deposit. August 11, 2023, Part 1
We have a new podcast! It’s called Universe Of Art, and it’s all about artists who use science to bring their creations to the next level. Listen on Apple Podcasts, Spotify, or wherever you get your podcasts.   Devastating Fires Might Become More Common In Hawaii As of Friday mor ... Show More
45m 11s
Jan 2025
Combatting Climate Anxiety through Community Science
It’s easy to feel overwhelmed with the news these days and to fear for the future. What if you could interrupt doomscrolling and contribute to conservation at the same time? That’s the idea behind programs like Adventure Scientists, eBird and iNaturalist. Guest Gregg Treinish, fo ... Show More
14m 34s