logo
episode-header-image
Jul 2024
23m 4s

Audio long read: Hope, despair and CRISP...

SPRINGER NATURE LIMITED
About this episode

In India, a group of researchers raced to develop a CRISPR-based genome editing therapy to save the life of a young woman with a rare neurodegenerative disease. Despite a valiant effort, the pace of research was ultimately too slow to save her life. While many are convinced that these therapies could offer hope to those with overlooked genetic conditions, it will likely take years to develop the techniques needed to quickly create bespoke treatments, something people in need don't have.


This is an audio version of our Feature: Hope, despair and CRISPR — the race to save one woman’s life


Hosted on Acast. See acast.com/privacy for more information.

Up next
Aug 20
Fusion energy gets a boost from cold fusion chemistry
00:46 Electrochemical fusionResearchers have used electrochemistry to increase the rates of nuclear fusion reactions in a desktop reactor. Fusion energy promises abundant clean energy, but fusion events are rare, hindering progress. Now, inspired by the controversial claim of col ... Show More
19m 57s
Aug 15
Controversial climate report from Trump team galvanizes scientists into action
In this Podcast Extra, we discuss a report released by the US Department of Energy, which concluded that global warming is “less damaging economically than commonly believed”. However, many researchers say that the report misrepresents decades of climate science.We discuss how sc ... Show More
13m 5s
Aug 13
Sun-powered flyers could explore the mysterious mesosphere
00:46 Tiny solar flyerResearchers have used a phenomenon known as thermal transpiration to create a solar-powered flying device that can stay aloft without any moving parts. The diminutive device, just one centimetre across, consists of two thin, perforated membranes that allow a ... Show More
31m 53s
Recommended Episodes
Oct 2024
EP 159: Engineering macrophages to tackle rare disease with Noam Baumatz of Noga Therapeutics
In this episode, we’re joined by Noam Baumatz, CEO and Co-Founder of Noga Therapeutics, a company dedicated to developing gene therapies for rare and severe diseases through engineering macrophages. Motivated by his highly personal experience of rare disease, Noam founded Noga to ... Show More
44m 17s
Oct 2024
The Future of Humanity? How CRISPR Could Change Life Forever
The Future of Humanity? How CRISPR Could Change Life Forever" - In this episode, we explore the groundbreaking world of CRISPR and genetic engineering, technologies that promise to reshape our future. Discover how CRISPR's precision editing could eliminate genetic diseases, enhan ... Show More
15m 44s
Apr 2023
The New Age of CRISPR
CRISPR has emerged as a powerful tool for altering DNA sequences with incredible precision, opening up new avenues of research into the treatment of disease. In this episode, we explore the science behind CRISPR, as well as its potential. From curing genetic disorders to creating ... Show More
27m 40s
Oct 2024
Engineering an Open Source CRISPR with Aadyot Bhatnagar
CRISPR is a powerful tool in biotechnology that allows scientists to precisely edit genes, much like editing lines of code in a computer program. Just as developers can remove or alter specific parts of a code to fix bugs or enhance functionality, CRISPR enables researchers to mo ... Show More
32m 57s
May 2023
CRISPR | The Future of Genetic Engineering
In this episode, Dr Matt and Dr Mike discuss how humans realised that bacteria could fight off viruses using sequences in their DNA called, CRISPR. Today, CRISPR technology is being used to cure cancer and investigate the cause of genetic disease.  For a video of Dr Mike teaching ... Show More
1h 22m
Oct 2023
How I Took 9 Years off My Age: Live From Toronto with Gene Therapy Pioneer Dr. Adeel Khan : 1098
In this episode, we're broadcasting live from Toronto with Dr. Adeel Khan, a leading figure in the field of gene and cell therapies. Dr. Adeel Khan, who holds an M.D. and is a Canadian Board Certified Physician, specializes in regenerative and cellular medicine. He is also a reco ... Show More
1h 50m
May 23
The Gene-Editing Breakthrough That Saved a Baby’s Life
Last year, Kyle and Nicole Muldoon welcomed their baby KJ into the world. Almost immediately, doctors realized something was wrong. KJ had been born with a genetic mutation that made it impossible to regulate the amount of ammonia in his system. The rare disease had the potential ... Show More
51m 20s
Mar 2025
The Life Scientific - Ijeoma Uchegbu
Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects.Ijeoma Uchegbu, Professor of Pharmaceutical Nanoscience at Uni ... Show More
26m 28s
Jul 2024
My quest to cure prion disease — before it's too late | Sonia Vallabh
Biomedical researcher Sonia Vallabh's life was turned upside down when she learned she had the genetic mutation for a rare and fatal illness, prion disease, that could strike at any time. Thirteen years later, her search for a cure has led to new insights about how to catch and p ... Show More
18m 23s
May 2022
S2 002: Rudy Benfredj at Mendelian ➡️ Rare diseases, genetics, AI. 🧬🤖🏥
A computer scientist fascinated by the genetic code and its application to rare disease, Rudy Benfredj moved into healthtech and cofounded Mendelian. Mendelscan, their core technology helps identify patients at risk of developing a rare disease early. We touch on the patient’s di ... Show More
31m 23s