Mar 2026
What Houses, Garbage, and Trucks Teach Us About Aging with Dr. Uri Alon
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Uri Alon, Professor at Weizmann Institute of Science. They explore a systems view of aging that treats longevity as a solvable model, not a grab bag of disconnected theories.Uri explains aging with a ... Show More
1h 4m
Mar 2026
Born to Live Longer? Inside the Genetics and Biology of Centenarians
In this episode of Longevity by Design, host Dr. Gil Blander sits down with Dr. Paola Sebastiani, Professor of Biostatistics at Tufts Clinical and Translational Science Institute. They explore what centenarians reveal about reaching 100, and why there’s no single longevity gene.P ... Show More
1h 1m
Dec 2023
How & Why You Age, And What It Takes To Be 'Young Forever' – Mark Hyman, M.D. - End of Year Best-Of Episode! : 1118
<p>In this special end-of-year "best of" episode, you'll learn the Top 10 hallmarks of aging, the role of functional medicine in restoring and reversing aging, and the many practical ways you can promote your own longevity.</p><p>Mark Hyman, M.D., joins Dave in Austin to talk all ... Show More
1h 8m
Dec 2021
The Biology of Slowing & Reversing Aging | Dr. David Sinclair
In this episode, I am joined by Dr. David Sinclair, tenured Professor of Genetics at Harvard Medical School and an expert researcher in the field of longevity. Dr. Sinclair is also the author of the book Lifespan: Why We Age & Why We Don't Have To, and the host of the Lifespan Po ... Show More
2h 7m
Dec 2024
Reverse Aging Now: The Latest Longevity Breakthroughs | Dr. Eric Verdin
What if aging wasn’t inevitable, but something you could slow—or even reverse? In this episode of “The Dr. Hyman Show,” Dr. Eric Verdin, the president of the Buck Institute for Research on Aging, and I dive deep into the science of longevity. Discover how lifestyle choices, mitoc ... Show More
1h 9m
Jan 2022
The Science Behind Why We Age | Episode 1
In this episode, Dr. David Sinclair and co-host Matthew LaPlante discuss why we age. In doing so, they discuss organisms that have extreme longevity, the genes that control aging (mTOR, AMPK, Sirtuins), the role of sirtuin proteins as epigenetic regulators of aging, the process o ... Show More
1h 2m
Oct 2025
Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair
In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, reg ... Show More
39m 7s
Sep 2019
We Can Slow Down Aging Right Now – David Sinclair, Ph.D. : 626
<p>In this episode of Bulletproof Radio,my guest is an Australian biologist best known for his research on lifespan extension and the treatment of diseases for aging.</p><p>“I'm a scientist,” says David Sinclair, Ph.D., “and I'm trying to figure this stuff out before time ru ... Show More
1h 11m
Aug 2024
E120: Inflammatory Diseases and Anti-Aging
<p>Did you know that the way your skin ages may indicate the presence of neurodegenerative diseases, such as Alzheimer or Parkinson’s diseases, lung aging and cardiovascular diseases?</p>
<p>This and much more in an extremely interesting episode presented by Prof. Jan Gutermuth, ... Show More
21m 9s
Dec 2021
The Emerging Science Of Longevity with Peter Diamandis
This episode is brought to you by BiOptimizers, Athletic Greens, and Rupa Health. What if I told you we’ll reach a point in time where scientific breakthroughs will extend our lives by more than a year, for every year we are alive? This is called longevity escape velocity, and so ... Show More
1h 17m
Feb 2022
Biotracking, Age Reversal & Other Advanced Health Technologies | Episode 8
In the final episode of this season, Dr. David Sinclair and Matthew LaPlante focus on current and near-future technologies relevant to health and aging. In addition to discussing the utility of wearable sensors and biological age measurements, they highlight innovative research a ... Show More
1h 9m
On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his groundbreaking research on inflammaging— uncovering how chronic, low-grade inflammatio ... Show More
