In this episode, we are excited to welcome George Church, Professor at Harvard Medical School and MIT, and Co-founder of Eugit Therapeutics, Colossal Biosciences, Arrived AI, and eGenesis. He is also the Director of PersonalGenomes.org, the world's only open-access information hub for human genomic, environmental, and trait data, as well as an IARPA BRAIN Pr ... Show More
Aug 21
EP 201: The gene therapy playbook: Successes, setbacks, and the path forward with Richard Wilson of Astellas
This week on The Genetics Podcast, Patrick is joined by Richard Wilson, Senior Vice President, Primary Focus Lead of Genetic Regulation at Astellas. They discuss where the gene therapy field stands today, diving into successes, persistent barriers, regulatory considerations, manu ... Show More
47m 28s
Aug 14
EP 200: From predictions to breakthroughs in genetics and biotech
This week on The Genetics Podcast, we celebrate our 200th episode with a look back at some of the earliest episodes, particularly ones that foresaw major trends or went on to spark real-world impact. These include Eric Topol’s early predictions about AI in healthcare, Laurence Re ... Show More
34m 40s
Aug 7
EP 199: Functional genomics at scale: Using in vivo perturbations to study genetic risk variants in the brain with Xin Jin of Scripps Research Institute
This week on The Genetics Podcast, Patrick is joined by Xin Jin, Associate Professor in the Department of Neuroscience at The Scripps Research Institute. They discuss how in vivo Perturb-seq enables scalable and high-resolution modeling of neurogenetic disorders like autism, how ... Show More
36m 31s
Aug 2022
How Reprogramming Our Genes Can Extend Our Lives with George Church
This episode is brought to you by Rupa Health, Cozy Earth, and InsideTracker. All living things are programmed with a certain lifespan, which can be dramatically different from species to species. Humans now, in general, live twice as long as our ancestors, thanks to environmenta ... Show More
1h 14m
Jul 2018
a16z Podcast: The Scientific Revolution of Ancient DNA
with Jorge Conde (@jorgecondebio), David Reich, and Hanne Tidnam (@omnivorousread) Trying to reconstruct the deep past of ancient humans out of present-day people has until now been like trying to reconstruct a bomb explosion in a room from bits of shrapnel, says David Reich, Pro ... Show More
31m 38s
Feb 2023
Dr. Oded Rechavi: Genes & the Inheritance of Memories Across Generations
In this episode, my guest is Oded Rechavi, Ph.D., professor of neurobiology at Tel Aviv University and expert in how genes are inherited, how experiences shape genes and remarkably, how some memories of experiences can be passed via genes to offspring. We discuss his research cha ... Show More
2h 27m
Jul 2020
#113 – Manolis Kellis: Human Genome and Evolutionary Dynamics
Manolis Kellis is a professor at MIT and head of the MIT Computational Biology Group. He is interested in understanding the human genome from a computational, evolutionary, biological, and other cross-disciplinary perspectives.
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2h 29m
Apr 2023
Brian Villmoare, "The Evolution of Everything: The Patterns and Causes of Big History" (Cambridge UP, 2023)
Big History seeks to retell the human story in light of scientific advances by such methods as radiocarbon dating and genetic analysis. Brian Villmoare's book The Evolution of Everything: The Patterns and Causes of Big History (Cambridge UP, 2023) provides a deep, causal view of ... Show More
1 h