logo
episode-header-image
Mar 2024
56m 15s

H3K36me3, H4K16ac and Cryptic Transcript...

Active Motif
About this episode
tail spinning
Up next
Jan 15
Spatial-Omics and Machine Learning in Muscle Stem Cell Repair (Will Wang)
In this episode of the Epigenetics Podcast, we talked with Will Wang from Sanford Burnham Prebys about his work on muscle stem cell repair, regeneration, and aging, exploring spatial-omics and machine learning. We begin our conversation by exploring the traditional concepts of sp ... Show More
55m 41s
Dec 18
The Future of Protein–DNA Mapping (Mitch Guttman)
In this episode of the Epigenetics Podcast, we talked with Mitch Guttman from Caltec about ChIP-DIP (ChIP-Done In Parallel). ChIP-DIP is a newly developed approach for high-resolution protein–DNA interaction mapping. The method uses antibody-guided isolation of denaturant-insolub ... Show More
1h 2m
Dec 4
Chromatin Modifiers and Their Roles in Brain Development (Fides Zenk)
In this episode of the Epigenetics Podcast, we talked with Fides Zenk from the École polytechnique fédérale de Lausanne about her work on transgenerational inheritance in Drosophila and brain organoids for human development insights. Dr. Zenk begins by sharing her journey into th ... Show More
28m 26s
Recommended Episodes
Apr 2022
#072 Morgan Levine, PhD, on PhenoAge and the Epigenetics of Age Acceleration — can we change the pace?
Morgan Levine, Ph.D., developed the phenotypic aging clock called PhenoAge and is a Founding Principal Investigator at Altos Labs, a biotech company that seeks to understand the mechanisms that drive the aging process and age-related diseases with the hope of identifying possible ... Show More
1h 29m
May 2025
Aging
Aging is an essential topic for the MCAT, and in this episode, we’ll explore it from multiple angles. We start with the biological aspects of aging, including key processes like telomere shortening, cell senescence, and mitochondrial dysfunction—each providing insight into how an ... Show More
30m 51s
Mar 2025
The Science, Evolution, and Future of Lifespan and Healthspan with Dr. Michael Ringel
<p>On this episode of Longevity by Design, Dr. Gil Blander speaks with Dr. Michael Ringel, COO of Life Biosciences, about the science of aging and longevity. Michael discusses how evolution influences lifespan and why aging occurs. He explains the trade-off between resource alloc ... Show More
1h 12m
Jan 2025
#333 ‒ Longevity roundtable — the science of aging, geroprotective molecules, lifestyle interventions, challenges in research, and more | Steven Austad, Matt Kaeberlein, Richard Miller
tail spinning
2h 41m
Sep 2024
The Surprising Link Between Space Travel and Aging with Dr. David Furman
<p>On this episode of Longevity by Design, Ashley Reaver, MS, RD, CSSD, and Dr. Gil Blander, delve into the intricate world of the immune system and its impact on aging with Dr. David Furman, Associate Professor at the Buck Institute for Research on Aging. David discusses his gro ... Show More
1h 8m
Feb 2025
Menopause's Role in Human Evolution: The Grandmother Hypothesis with Kristen Hawkes
<p class="p1">Kristen Hawkes' "Grandmother Hypothesis" provides a fascinating perspective on human evolution, menopause, and the unique social structures of humans. This theory posits that the long post-reproductive lifespan of women evolved because grandmothers played a critical ... Show More
1h 15m
Feb 2019
Biogerontology (AGING) with Caleb Finch
<p>How long can we live? How much of aging is genetics vs. environment? What does oral hygiene have to do with brain health? What causes Alzheimer’s? How do turtles and naked mole rats live so long? Are there any proven strategies for living a longer life? What's up with whiskey ... Show More
51m 49s
Sep 2021
David Sinclair: Reverse Aging & Extend Your Lifespan
David Sinclair (biologist, Professor of Genetics at Harvard Medical School, and author of Lifespan: Why We Age and Why We Don’t Have To) discusses ways we can extend our lifespan and the work he’s doing to slow and reverse aging brain cells. He details the best lifestyle changes ... Show More
1h 6m
Aug 2025
Evolution designed us to die fast; we can change that — Jacob Kimmel
Jacob Kimmel thinks he can find the transcription factors to reverse aging. We do a deep dive on why this might be plausible and why evolution hasn’t optimized for longevity. We also talk about why drug discovery has been getting exponentially harder, and what a new platform for ... Show More
1h 44m
Oct 11
342: The Microbiome, Pancreatic Cancer, and Sleep Quality
TWiM explains studies that show that the oral bacterial and fungal microbiome are risk factors for pancreatic cancer, and the gut microbiome and pyruvate metabolism of older adults are a link between sleep quality and frailty. Hosts: Vincent Racaniello, Michael Schmidt, and Miche ... Show More
53m 37s
Listen to millions of songs and podcasts on Anghami