•Only 30% of patients fully respond to the initial SSRI
•Ultimately less than 55% of people respond to any SSRI.
• WHY???
• SSRIs typically only work on the 5HTIA receptor, but multiple 5HT receptors are involved in mood regulation: 1, 2,
• SSRIs only impact one area of possible dysfunction
• Serotonin creation, secretion, absorption, distribution is impacte ... Show More
Oct 2022
Psychedelics & Neurostimulation for Brain Rewiring | Dr. Nolan Williams
In this episode, my guest is Nolan Williams, M.D., a triple board-certified psychiatrist, neurologist and professor of psychiatry and behavioral sciences at Stanford School of Medicine. He is also the Director of the Stanford Brain Stimulation Lab. We discuss clinical application ... Show More
2h 44m
Jan 2024
Episode 380: Dopamine Misconceptions
<p><strong>Hello friends!</strong></p> <p>In today's enlightening episode, we delve deep into the intricacies of neurotransmitters, specifically dopamine, and their impact on our behavior and mental health. We also touch on trichotillomania and the role of medications like Wellbu ... Show More
26m 43s
Jun 2023
The Science of MDMA & Its Therapeutic Uses: Benefits & Risks
In this episode, I discuss Methylenedioxymethamphetamine (MDMA), which is also commonly known as “ecstasy” or “molly,” including how it works in the brain to cause short- and long- term-shifts in emotional processing and its clinical applications for the treatment of post-traum ... Show More
2h 13m
May 2023
Adderall, Stimulants & Modafinil for ADHD: Short- & Long-Term Effects
In this episode, I explain how medications such as Adderall, Ritalin, Vyvanse and other stimulants work to increase focus and treat attention-deficit/hyperactivity disorder (ADHD). I explain the brain circuits involved in focus and the key roles dopamine and norepinephrine play i ... Show More
1h 58m