Short Answer: While the body will tend to use TMG for methylation in the fasting state, it is normally found in food, so you should be able to absorb it with meals and hold on to it for later use, much as we do with folate.
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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.
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Chris Masterjohn, PhD, is the Founder and Scientific Director of the mitochondria test Mitome.