Glipizide, or Glucotrol, is a sulfonylurea used for the treatment of Type 2 Diabetes. Pharmacologically, glipizide acts by stimulating beta-cells in the pancreas to release insulin. Specifically, glipizide will block the opening of ATP-sensitive potassium channels on the plasma membrane of beta-cells on the pancreas. The result of that is depolarization, whi ... Show More
Nov 20
Glycopyrrolate Pharmacology
Glycopyrrolate is an anticholinergic medication commonly used to reduce excessive secretions, particularly in palliative care, postoperative settings, and certain neurologic conditions. It works by blocking acetylcholine at muscarinic receptors, which decreases salivary and respi ... Show More
11m 47s
Nov 13
Bisacodyl (Dulcolax) Pharmacology
Bisacodyl, commonly known by the brand name Dulcolax, is a stimulant laxative widely used for short-term relief of constipation and bowel preparation before procedures. It works by directly stimulating the enteric nerves in the colon, increasing peristalsis, and promoting bowel e ... Show More
15m 53s
Jun 2024
#525: Cholesterol-Lowering Medication – Dr. Paddy Barrett
<p>Cholesterol-lowering medications, particularly statins, play a pivotal role in reducing low-density lipoprotein cholesterol (LDL-C) and apolipoprotein B (apoB) concentrations, which are causal markers in atherosclerosis development. The efficacy of these medications is well-do ... Show More
48m 29s
Jan 2023
#238 – AMA #43: Understanding apoB, LDL-C, Lp(a), and insulin as risk factors for cardiovascular disease
<p><a href= "https://peterattiamd.com/ama43/?utm_source=podcast-feed&utm_medium=referral&utm_campaign=230116-pod-ama43&utm_content=230116-pod-ama43-podfeed"> View the Show Notes Page for This Episode</a></p> <p><a href= "https://peterattiamd.com/subscribe/?utm_source=podcast-feed ... Show More
24m 23s