In this episode, Sam Ashoo, MD and Dr. Syeda Maria Muzammil, MD discuss the August 2026 Emergency Medicine Practice article, Emergency Department Management of Postthrombolysis Intracranial Hemorrhage.
- 0:25 – Intro & sponsor message
- 1:18 – Guest introduction: Dr. Maria Muzammil
- 2:24 – Timeframe for post-thrombolysis hemorrhage & ED/ICU boarding considerations
- 4:46 – Thrombolysis eligibility criteria & contraindications
- 5:46 – Incidence rates & symptomatic vs. asymptomatic hemorrhage
- 7:09 – Pathophysiology & risk factors for post-thrombolytic ICH
- 10:18 – Combining IV thrombolysis with endovascular thrombectomy
- 12:33 – Post-treatment monitoring protocols & neurological exam frequency
- 15:02 – Differentiating hemorrhage from other causes of neurological decline
- 18:34 – Initial ED steps
- 20:35 – Heidelberg classification of hemorrhage types
- 21:60 – Follow-up imaging
- 25:27 – Treatment of confirmed hemorrhage
- 30:10 – Platelet transfusion guidance
- 32:39 – Delayed hemorrhage & treatment timing considerations
- 34:21 – Blood pressure management goals post-hemorrhage
- 37:20 – Special populations
- 38:48 – Summary of ED management algorithm
- 40:48 – Closing remarks
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