About this episode
Jan 14
E273 - Busting Myths About Antidepressants with Dr. Jeffrey Strawn
In this episode, Dr. Andy Cutler and Dr. Jeff Strawn unpack common misconceptions that complicate real-world use of antidepressants. They review evidence on efficacy, suicidality risk, mechanisms, and early side effects, and discuss how to navigate hesitancy and misinformation. T ... Show More
53m 9s
Dec 31
E272 - Our Most Downloaded Episode of 2025: Borderline Personality Disorder with Dr. Carla Sharp
As 2025 comes to an end, we revisit our most downloaded episode of the year. Join Dr. Andy Cutler and Dr. Carla Sharp as they explore the current conceptualization of borderline personality disorder (BPD), including diagnostic challenges, evidence-based treatments, and strategies ... Show More
1 h
Dec 3
E270 - (CME) Complex Depression: Treating Beyond the Standard Algorithm
In this CME episode, Dr. Andy Cutler talks with Drs. Stephen Stahl and Roger McIntyre about recognizing and managing complex depression, particularly major depressive episodes with mixed or anxious features. They discuss how these specifiers affect diagnosis, symptom severity, an ... Show More
1 h
Oct 2024
Treating Mental Health Differently | Dr. John How
<h2>Resetting the Nervous System</h2><p>In this episode of the Dr. Gabrielle Lyon Show, we dive deep into groundbreaking approaches for treating PTSD, anxiety, and depression with Dr. John How, an emergency physician turned mental health advocate. Dr. How introduces us to the Ste ... Show More
1h 13m
May 2023
Psychotherapy for Psychosis with Dr. Michael Garrett
In this week's episode of the podcast, we interview Dr. Michael Garrett, Professor Emeritus of Clinical Psychiatry and former Vice Chair and Director of Psychotherapy Education at SUNY Downstate Medical Center, Brooklyn, NY. He also wrote a book called, Psychotherapy for Psychosi ... Show More
1h 33m
Apr 2021
Depression in adults
Depression can describe both a mood and an illness. Major depressive disorder is a clinical syndrome involving mood, neurovegetative functions, cognition, and behaviour. It affects 5% to 10% of patients in the primary care setting. Dean F. MacKinnon, Associate Professor, Psychiat ... Show More
19m 56s
Feb 2025
Harvard Psychiatrist: How To Heal Your Mind With Your Diet - The Scientific Connection Between Nutrition & Mental Health
1h 37m
Jul 2021
Persistent depressive disorder
Persistent depressive disorder is a category that includes various forms of chronic depression in which depressive symptoms are present 'more days than not' over at least a 2-year period (1 year in children and adolescents). David J. Hellerstein, Professor of Clinical Psychiatry, ... Show More
18m 57s
Dec 2023
200 Episodes Later: A Journey Through Psychiatry with Dr. Puder
Join us today on the 200th episode of the podcast, as Dr. Puder sits down with Dr. Mark Mullen to discuss the podcast, answer some questions about his personal journey in psychiatry, and reflect on some of his favorite episodes. Dr. Mark Mullen is a 4th year psychiatry resident a ... Show More
1h 17m
Apr 2025
Transference Focused Psychotherapy & Personality Disorders with Dr. Otto Kernberg
In this episode, Dr. Otto Kernberg, a pioneer of Transference-Focused Psychotherapy (TFP), discusses personality disorders through a psychoanalytic lens. Explore key insights into Borderline Personality Disorder (BPD), identity diffusion, primitive defense mechanisms such as spli ... Show More
1h 28m
Feb 2025
432 SelfWork: Doctors and Depression: A Conversation with Dr. Pam Buchanan
Today the focus is on doctors and depression, with Dr. Pamela Buchanan as my guest, in a second episode in the "Careers That Kill" series, discussing medical providers, the pandemic, and depression. She's a board-certified physician, speaker and thought leader dedicated to transf ... Show More
34m 15s
Sep 2025
How to Believe in Yourself: Carl Rogers and Humanistic Psychology
Dr. Rick and Forrest explore humanistic psychology, the mid-20th century movement that redefined how therapists relate to clients. It challenged the pessimism of Freud and the mechanism of behaviorism, offering a more hopeful alternative: that our nature is fundamentally good, an ... Show More
1h 21m
Jun 2025
Keto and Metabolic Treatments for Mental Health w/Dr. Chris Palmer
<p>Learn the skills to Regulate your Emotions, join the membership: <a href='https://courses.therapyinanutshell.com/membership'>https://courses.therapyinanutshell.com/membership</a></p>
<p>The speaker discusses the metabolic theory of mental health, suggesting that brain disorder ... Show More
28m 47s
Join Drs. Andy Cutler and Roger McIntyre as they discuss the most significant advancements in psychopharmacology over the past year. Their conversation highlights groundbreaking developments and innovations in the field of psychiatry.
Roger McIntyre, MD, FRCPC, is a globally recognized psychiatrist and psychopharmacologist who holds pivotal roles in academia, research, and leadership. His research primarily focuses on the phenomenology, neurobiology, and development of novel therapeutics for mood disorders. Dr. McIntyre is currently a Professor of Psychiatry and Pharmacology at the University of Toronto.
Andrew J. Cutler, MD, is a distinguished psychiatrist and researcher with extensive experience in clinical trials and psychopharmacology. He currently serves as the Chief Medical Officer of Neuroscience Education Institute and holds the position of Clinical Associate Professor of Psychiatry at SUNY Upstate Medical University in Syracuse, New York.
Thanarajah ES et al. Soft drink consumption and depression mediated by gut microbiome alterations. JAMA Psychiatry 2025;82(11):1095–1102. doi:10.1001/jamapsychiatry.2025.2579
Durgam S et al. Lumateperone as adjunctive therapy in patients with major depressive disorder: results from a randomized, double-blind, phase 3 trial. J Clin Psychiatry 2025;86(4):25m15848. doi: 10.4088/JCP.25m15848
Hendershot CS et al. Once-weekly semaglutide in adults with alcohol use disorder: a randomized clinical trial. JAMA Psychiatry 2025;82(4):395–405. doi: 10.1001/jamapsychiatry.2024.4789
Aron L et al. Lithium deficiency and the onset of Alzheimer's disease. Nature 2025;645:712–21. doi: 10.1038/s41586-025-09335-x
Interested in Psychopharmacology? Learn about the NEI Master Psychopharmacology Program: https://nei.global/mpp
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<p><a href="https://lewishowes.com/tour" target="_blank">I'm going on tour! Come see The School of Greatness LIVE in person!</a></p><p><a href="https://lewishowes.com/money" target="_blank">Get my new book Make Money Easy here!</a></p><p>What if the root cause of mental health di ... Show More
