logo
episode-header-image
About this episode
Senna is a stimulant laxative. Its pharmacological activity comes from natural compounds called sennosides. Metabolites act locally in the colon to stimulate peristalsis, thereby accelerating bowel movements. While osmotic laxatives are generally considered first-line laxative agents, this makes senna a useful alternative for the short-term treatment of cons ... Show More
Up next
Yesterday
Cefepime Pharmacology
Cefepime is a fourth-generation cephalosporin antibiotic with broad-spectrum activity against both gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. It works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, lea ... Show More
12m 28s
Oct 2
Midodrine Pharmacology Podcast
Midodrine is an oral alpha-1 agonist most commonly used for the treatment of symptomatic orthostatic hypotension. Its mechanism of action is through peripheral vasoconstriction, which helps increase blood pressure. Because of its short duration of action, it is typically dosed th ... Show More
12m 11s
Sep 25
Piperacillin/Tazobactam Pharmacology
Zosyn (piperacillin/tazobactam) is a broad-spectrum β-lactam/β-lactamase inhibitor combination used widely in hospitals. Piperacillin covers gram-positive, gram-negative, and anaerobic bacteria, while tazobactam helps protect against β-lactamase breakdown. It is commonly used for ... Show More
13m 18s
Recommended Episodes
Jul 2024
382. SGLT Inhibitors: The Data Supporting SGLT Inhibition with Dr. Muthiah Vaduganathan
CardioNerds Dr. Rick Ferraro, Dr. Gurleen Kaur, and Dr. Maryam Barkhordarian discuss the evidence and data supporting SGLT inhibition for cardiovascular and kidney health outcomes with expert faculty Dr. Muthu Vaduganathan. They discuss the role of SGLT inhibitors in different po ... Show More
24m 23s
Feb 2025
410. Case Report: A Curious Case of Refractory Ventricular Tachycardia – Rutgers-Robert Wood Johnson
CardioNerds (Dr. Colin Blumenthal and Dr. Saahil Jumkhawala) join Dr. Rohan Ganti, Dr. Nikita Mishra, and Dr. Jorge Naranjo from the Rutgers – Robert Wood Johnson program for a college basketball game, as the buzz around campus is high. They discuss the following case involving a ... Show More
40m 13s
Mar 2025
412: The Biology of Transthyretin amyloid cardiomyopathy (ATTR-CM) with Dr. Daniel Judge
CardioNerds Cardiac Amyloidosis Series Chair Dr. Rick Ferraro and Episode Lead Dr. Anna Radakrishnan discuss the biology of transthyretin amyloid cardiomyopathy (ATTR-CM ) with Dr. Daniel Judge. Notes were drafted by Dr. Anna Radakrishnan. The audio was engineered by student Dr. ... Show More
13m 1s
Jan 2024
Supplement Ingredients: N-Acetyl-Cysteine (NAC) - A Versatile Supplement for Lung, Liver, and Brain Health
This podcast discusses the benefits of N-Acetyl-Cysteine (NAC), a liver antioxidant that reduces inflammation in the body.  NAC is a sulfur-based tripeptide that can detoxify the body and support liver health. It also serves as a precursor to glutathione, a master antioxidant.   ... Show More
1m 56s
Mar 2025
DON'T IGNORE THIS IF YOU'RE OVER 50!!!
All it takes is a small amount of oxidative stress to the eye's lens to develop a cataract. A healthy lens is composed of an organized protein called crystallin. When this tissue becomes damaged, it is not replaced. Glycation can damage the lens of the eye. It results from sugar ... Show More
6m 53s
Jul 23
192 - Opioids Optional: Journavx, the New Acute Pain Management Alternative
In this episode, we discuss the evidence, safety, and place in therapy of Journavx® (suzetrigine), a newly approved analgesic with a unique non-opioid mechanism of action and additional considerations for its use. Key Concepts Suzetrigine is a first in its class NaV1.8 sodium cha ... Show More
33m 57s
Sep 26
Advancing Real World Wound Care with Dr. Jaideep Banerjee of Smith+Nephew
This episode features Dr. Jaideep Banerjee, Director of Global Clinical & Medical Affairs at Smith+Nephew, discussing the challenges of chronic wound care, the importance of standardized evidence-based practices, and insights from his recent large-scale study on enzymatic debride ... Show More
19m 35s
Sep 25
Urinary Tract Malignancies
Ninja Nerds!In this episode of the Ninja Nerd Podcast, Zach and Rob dive into the essential clinical and pathophysiologic features of urinary tract malignancies, beginning with renal cell carcinoma (RCC) and followed by urothelial carcinoma of the bladder.We start with a patient ... Show More
29m 41s
Dec 2023
Supplement Ingredients: Resveratrol - The Antioxidant in Red Wine
The podcast discusses the benefits of resveratrol, a plant-based extract found in grapes, cacao, and peanuts. It is known for its antioxidant properties and has been shown to promote heart, liver, and brain health. Taking resveratrol daily can also help with blood sugar and insul ... Show More
1m 56s