In this episode, we begin with discussing our article of the week which comes from JAMA Network Open and is entitled “Oral vancomycin for prevention of recurrent clostridioides difficile infection: A randomized clinical trial.” Then, we discuss Venus Williams’ triumphant return to tennis and her advocacy for fibroid awareness and insurance reform. Then we turn to Matt McGorry’s long COVID journey and the scientific breakthrough that redefines the condition as biologically diverse. Next, we examine a global crisis of contaminated pediatric medicines and the WHO’s urgent call for regulatory action. Finally, we highlight Tammy Slaton’s 500-pound transformation and the lingering barriers that shape access to bariatric surgery in the United States.