Part 223 – Mark Sisson on Metabolic Flex...

Mark Sisson, 72 and still shredded, returns to Peak Human for a powerful conversation on what real healthspan looks like — not chasing 180 years with futuristic tech, but thriving into your 90s with energy, strength, and vitality. As the founder of the Primal Blueprint, Mark brings decades of wisdom on metabolic flexibility, minimalist training, and practical ancestral living.

In this episode, Brian and Mark discuss how to optimize metabolism, how to train smarter (not harder), the real deal with fiber, alcohol, hydration, and carbs — and why metabolic flexibility is the key to enjoying life without strict rules, guilt, or orthorexia.

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Show Notes:

02:00 The Primal Blueprint and 25 Years of Low Carb Living

04:00 Minimum Effective Dose – Why Mark Hates Overtraining

11:30 Redefining Metabolic Flexibility

14:00 Burning Carbs and Fat – The Joy of Not Being Rigid

18:00 Why Unsustainable Diets Always Fail

20:30 The European Bread Exception – Healing the Gut for Freedom

24:00 Alcohol, Red Wine & the Spectrum of Acceptable Foods

27:30 Fiber is Overrated – Healing IBS with Collagen & Meat

34:00 What Stool Really Is – Busting Fiber Myths

39:00 The Problem with Sugar Diets & Misguided Trends

44:00 You’re Not Dehydrated – The Hydration Hype Exposed

49:00 Do We Really Need Electrolytes All the Time?

52:00 Sunlight: Powerful, But Not Without Risk