Loxapine is a first-generation (typical) antipsychotic with dopamine D2 receptor antagonism as its primary mechanism, though it also has affinity for serotonin 5-HT2A receptors, making its pharmacology somewhat atypical.
Loxapine is available in multiple formulations, including oral capsules and an inhalation powder, the latter approved specifically for a ... Show More
Aug 7
Itraconazole Pharmacology
In this episode, we break down itraconazole—a potent antifungal with a lot of baggage. If you’re a pharmacist, clinician, or student who needs to understand how this drug works and why it can be tricky to use, this episode is for you. We start with the basics. Itraconazole blocks ... Show More
10m 50s
Aug 2024
184 - Drop it Like it’s Hot! Deprescribing Pharmacotherapy When Appropriate
In this episode, we discuss the approach to deprescribing for several drugs such as benzodiazepine receptor agonists, cholinesterase inhibitors, memantine, antipsychotics, and antihyperglycemics. Key Concepts Medication appropriateness including indication and risk vs. benefit sh ... Show More
38m 50s
Nov 2023
Pharmacology of Mood Disorders Part 1
A few weeks ago, MS3 Bilal Rana hosted an episode on Mood Disorders. This is a two-part follow-up to that episode, with a packed and powerful review of the pharmacology of mood disorders – what are the drugs we use to treat mood disorders, and how do they work? In part 1, we cove ... Show More
1h 4m