Dr. Rizwan Romee is a Oncologist at the Dana-Farber Cancer Institute and Associate Professor at Harvard Medical School, where his research focuses on genetically manipulating NK cells to enhance their anti-tumor function. He talks about advances and challenges in engineering NK cells for cancer therapy. He also discusses using E. coli to deliver immune-activ ... Show More
May 20
Ep. 105: IMMUNOLOGY2025™: On the Ground
In May 2025, we attended IMMUNOLOGY2025™, the annual meeting of the American Association of Immunologists, in Honolulu. We chat with delegates about their research and impressions of the meeting. They discuss their reasons for attending, the most memorable research, and their exp ... Show More
32m 41s
Nov 2024
CAR T Cells and T-Cell Therapies for Cancer
CAR T cells are genetically engineered to express a receptor that recognizes and kills tumor cells. CAR T-cell products are now FDA approved for 6 hematologic malignancies. Author Jennifer N. Brudno, MD, National Cancer Institute, joins JAMA Deputy Editor Mary McGrae McDermott, M ... Show More
18m 22s
Jan 2025
The Interplay of Nutrition, Metabolic Pathways, and Epigenetic Regulation (Ferdinand von Meyenn)
In this episode of the Epigenetics Podcast, we talked with Ferdinand von Meyenn from ETH Zürich about his work on the interplay of nutrition, metabolic pathways, and epigenetic regulation. To start Dr. Meyenn recounts his pivotal research on DNA methylation in naive embryonic ste ... Show More
48m 5s
Sep 2024
EP 153: How genomics is re-writing the taxonomy of disease with Lon Cardon, President and CEO of The Jackson Laboratory
This week, Patrick welcomes President and CEO of The Jackson Laboratory, Lon Cardon. They discuss the rise of genome-wide association studies (GWAS) and how they changed the face of genetics research and why Lon took the plunge and moved from academia to industry in an era when i ... Show More
40m 25s
Oct 2024
Epigenetic Mechanisms of Mammalian Germ Cell Development (Mitinori Saitou)
In this episode of the Epigenetics Podcast, we talked with Mitinori Saitou from Kyoto University about his work on germ cell development, focusing on proteins like BLIMP1 and PRDM14, reprogramming iPSCs, and his vision to address infertility and genetic disorders through epigenet ... Show More
39m 49s
Feb 2009
TWiV #22 - Viral bioinformatics
In episode 22 of This Week in Virology, host Vincent Racaniello and guest host Chris Upton, a professor in the Department of Biochemistry and Microbiology at the University of Victoria in Vancouver, Canada, converse about hepatitis B in India, AIDS gene therapy with a ribozyme, a ... Show More
59m 2s
Jun 16
CDC Vaccine Panel Fired by RFK, Jr., Oceans Grow More Acidic, and Pangolins Threatened by Hunting
Robert F. Kennedy, Jr., has fired the experts on the Centers for Disease Control and Prevention’s vaccine advisory panel, sparking concern among public health officials. Ocean acidification has crossed a critical threshold, posing serious risks to marine life around the globe. An ... Show More
10m 14s
Jun 5
EP 190: Targeting regeneration to tackle Duchenne Muscular Dystrophy with Frank Gleeson of Satellos
Summary: This week on The Genetics Podcast, Patrick is joined by Frank Gleeson, co-founder and CEO of Satellos. They discuss Satellos’ novel approach to treating Duchenne Muscular Dystrophy by targeting muscle stem cell regeneration, how this fills a critical therapeutic gap, and ... Show More
48m 50s