This week, Patrick welcomes President and CEO of The Jackson Laboratory, Lon Cardon. They discuss the rise of genome-wide association studies (GWAS) and how they changed the face of genetics research and why Lon took the plunge and moved from academia to industry in an era when it was an unpopular choice. Plus, they cover the future of disease taxonomy and w ... Show More
Sep 24
EP 258: The mutations hiding in healthy tissues with Inigo Martincorena of the Wellcome Sanger Institute
This week on The Genetics Podcast, Patrick is joined by Dr. Inigo Martincorena, Group Leader at the Wellcome Sanger Institute. They discuss the discovery of widespread cancer-driver mutations in normal tissue, the role of somatic mutations in autoimmune disease, new sequencing te ... Show More
39m 14s
Sep 17
EP 257: Managing hereditary cancer risk and medical uncertainty with Marleah Dean Kruzel of the University of South Florida
This week on The Genetics Podcast, Patrick is joined by Dr. Marleah Dean Kruzel, Professor of Communication at the University of South Florida. They discuss her personal path from watching breast cancer move through her family to testing positive for a hereditary mutation herself ... Show More
39m 21s
Sep 10
EP 256: Cutting through the AI hype in drug discovery with Dave Hallett of Recursion
This week on The Genetics Podcast, Patrick is joined by Dr. David Hallett, Chief Scientific Officer at Recursion. They discuss the biggest shifts in drug discovery over Dave's three-decade career, where AI is genuinely transforming the field today versus where the hype outruns th ... Show More
40m 59s
May 2022
The DNA sequencing revolution
Fast and portable genome testing is unlocking the secrets to ourselves and the environment we live in.It's impact could lead us to fundamentally remake our approach to medicine, agriculture, the environment, conservation and our selves.In this episode we hear from Dr Lara Urban, ... Show More
18m 48s
Aug 2021
Discovery, Translation, and the State of Bio Today
<p>On this episode, we are taking a pulse-check on the state of the intersection between biology, healthcare, and technology with two scientists that sit at another intersection, that of academia and industry: Alexander Marson and Patrick Hsu, who are professors at UC San Francis ... Show More
33m 5s
Mar 2012
Genes and evolution - from populations to tumours
From whole populations to individual cancers, we're taking a look at genes and evolution. We're also talking about dogs and their diseases, shining a light on Van Gogh's sunflowers, and wondering whether the USB-sized DNA sequence is hope or hype. Plus we've got our gene of the m ... Show More
32m 40s