In this episode, we begin with a discussion about our article of the week. Our article of the week comes from The New England Journal of Medicine and is entitled “Twice-Yearly Lenacapavir for HIV Prevention in Men and Gender-Diverse Persons.” Then in the second half of the episode, we begin with a discussion about Billy Joel’s newly disclosed diagnosis of normal pressure hydrocephalus and what his case teaches us about spotting this reversible dementia mimic sooner. Then we take a closer look at model and advocate Gigi Robinson’s experience with hypermobile Ehlers-Danlos syndrome and how breast-reduction surgery slashed her pain while exposing persistent insurance hurdles. After that, we examine new research linking each 1 °C rise in Middle East and North African temperatures to a sharp surge in women’s cancer incidence and mortality. Finally, we discuss the discovery of West Nile virus fragments in UK mosquitoes and the public-health actions underway as climate change expands vector-borne threats.