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Apr 2025
1h 6m

The End of Cardio? Burn Fat & Boost VO₂ ...

Dave Asprey
About this episode

You’ve probably heard of HIIT—but have you heard of “REHIT?”  This isn’t just another workout trend...it’s a new science-backed way to train with maximum efficiency and zero wasted time. If you’re still jogging, you’re wasting hours for minimal results. 

In this episode of The Human Upgrade, Dave Asprey sits down with Ulrich Dempfle, German-trained engineer and co-founder of CAROL Bike, to dismantle outdated cardio advice and introduce the 5-minute protocol that’s obliterating fitness myths. 


Forget the treadmill grind. REHIT (Reduced Exertion High-Intensity Training) exercising delivers: 

• 12% VO₂ max increase

• 6x the fitness gains of daily jogging 

• 62% drop in diabetes risk 

• 5x more BDNF for brain power 

—all with just 8 minutes of effort per week. 


But was it? Ulrich unpacks the hard data, crushes the Zone 2 obsession, and shows how a brand-new way of exercising is giving explosive results—no matter your age or fitness level. 


What You’ll Learn in This Episode: 

• Why Zone 2 cardio is outdated advice for most people 

• The science of REHIT and how 2 sprints beat 2-hour workouts 

• The shocking data on VO₂ max, insulin sensitivity, and lifespan 

• How CAROL uses AI to personalize exercise for any age or ability 

• Why most people fail at fitness—and how to fix it 

• The real role of lactate, BDNF, and HRV in recovery and resilience 

• How perimenopausal women benefit more from REHIT than HIIT or jogging 

• Why adherence—not intensity—is the #1 predictor of results 

• What to do when you’re traveling or don’t have access to the tech 


Resources:  

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/ 

CAROL Bike Website and use code ‘DAVE’ for a discount –  https://carolbike.com/ 

CAROL Bike Instagram - https://www.instagram.com/thecarolbike/?hl=en 

2025 Biohacking Conference: https://biohackingconference.com/2025 

Danger Coffee: https://dangercoffee.com 

Dave Asprey’s Website: https://daveasprey.com 

Dave Asprey’s Linktree: https://linktr.ee/daveasprey 

Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com 

Own an Upgrade Labs: https://ownanupgradelabs.com 

Upgrade Labs: https://upgradelabs.com 

40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com 


Timestamps: 

00:00 Introduction to REHIT Training 

00:24 Meet Ulrich Dempfle: The Mind Behind CAROL Bike 

00:51 The Science and Benefits of REHIT 

01:44 Comparing Traditional Cardio to REHIT 

02:32 Dave Asprey’s Personal Fitness Journey 

03:43 The Efficiency of REHIT Training 

05:03 Practical Applications and Accessibility of REHIT 

08:22 Addressing Common Concerns and Misconceptions 

11:25 The Future of Fitness: REHIT and Beyond 

18:29 Scientific Validation and Real-World Results 

31:53 Clinical Trials and Tech Integration 

32:06 Upgrade Labs and CAROL Bike 

33:00 Mitochondrial Effectiveness and Insulin Sensitivity 

36:05 Zone Two Training vs. High-Intensity Training 

42:02 REHIT for Perimenopausal Women 

48:18 AI and Personalized Exercise 

57:52 Lactate and Exercise Benefits 

01:01:48 Interval Walking Training 

01:04:01 Conclusion and Future Insights 

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