How can AI help us understand and master deeply complex systems—from the game Go, which has 10 to the power 170 possible positions a player could pursue, or proteins, which, on average, can fold in 10 to the power 300 possible ways? This week, Reid and Aria are joined by Demis Hassabis. Demis is a British artificial intelligence researcher, co-founder, and C ... Show More
Sep 22
Trump’s Press Crackdown, Paramount Settles, and Anthropic’s $2 Trillion IPO
Kara and Scott unpack the Paramount–Warner Bros. Discovery settlement, the White House’s escalating fight with the press, and Amazon blocking Meta’s AI assistant. Then, they break down Trump's plans for an AI Force, whether Anthropic can pull off a $2 trillion IPO, and the stakes ... Show More
1h 12m
Sep 18
Zuck's AI Safety Pitch, Canada Turns to Europe, and Kash Patel on Bestiality
Kara and Scott debate Sydney Sweeney’s latest controversial ad. Raging Moderates co-host Jessica Tarlov joins to discuss Canada cozying up to Europe, and the art of political disagreement. Then, Universal's cold feet about the Elon Musk documentary, Mark Zuckerberg’s motives in t ... Show More
1h 6m
Sep 15
AI Panic: Dario’s Warning, Trump’s Dismissal, and OpenAI’s IPO Delay
Kara and Scott unpack the recent AI panic, as Dario Amodei calls for a slowdown, Donald Trump dismisses concerns, and Sam Altman says OpenAI won’t go public this year. Then, they discuss Mark Carney’s push for closer ties with the EU, and why Canada and the U.S. may not be gettin ... Show More
58m 17s
Jul 2025
#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games
Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep475-sc See below for timestamps, transcript, and to give f ... Show More
2h 34m
Mar 2022
The promise of AI with Demis Hassabis
Hannah wraps up the series by meeting DeepMind co-founder and CEO, Demis Hassabis. In an extended interview, Demis describes why he believes AGI is possible, how we can get there, and the problems he hopes it will solve. Along the way, he highlights the important role of consciou ... Show More
30m 28s
Feb 2024
Demis Hassabis — Scaling, superhuman AIs, AlphaZero atop LLMs, AlphaFold
Here is my episode with Demis Hassabis, CEO of Google DeepMindWe discuss:* Why scaling is an artform* Adding search, planning, & AlphaZero type training atop LLMs* Making sure rogue nations can't steal weights* The right way to align superhuman AIs and do an intelligence explosio ... Show More
1h 1m