How can AI help us understand and master deeply complex systems—from the game Go, which has 10 to the power 170 possible positions a player could pursue, or proteins, which, on average, can fold in 10 to the power 300 possible ways? This week, Reid and Aria are joined by Demis Hassabis. Demis is a British artificial intelligence researcher, co-founder, and C ... Show More
Yesterday
Michigan's Primary Drama, the DOJ's Next Boss, and Hillary Clinton Co-Hosts
Kara sits down with former Secretary of State Hillary Clinton for the first episode of Scott-Free August. They discuss Michigan's messy Democratic primary, state redistricting brawls, and Trump's gold-plated redecoration of the the presidency. Then — Todd Blanche's path to attorn ... Show More
1h 12m
Aug 4
RFK Jr.'s Bash Clash, AI's "Jurassic Park" Moment, and Elon's Midterm Millions
Kara and Scott break down RFK Jr.'s combative CNN interview with Dana Bash. Then, Anthropic joins OpenAI in revealing alarming AI hacking incidents, raising new questions about regulation and cybersecurity. Plus, Big Tech earnings, Elon Musk's midterm spending plans, and the Trum ... Show More
1h 8m
Jul 31
Mamdani’s Tax List, Zuck's Media Blitz, and SpaceX’s Trillion-Dollar Wipeout
Kara and Scott unpack Mayor Mamdani’s controversial luxury tax list, Mark Zuckerberg’s AI messaging campaign, and SpaceX’s trillion-dollar wipeout. Then, they discuss the growing divide over AI safety, Apple’s new leasing program, and calls for Mitch McConnell to prove he’s still ... Show More
1h 2m
Jul 2025
#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games
Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI. Thank you for listening ❤ Check out our sponsors: https://lexfridman.com/sponsors/ep475-sc See below for timestamps, transcript, and to give f ... Show More
2h 34m
Mar 2022
The promise of AI with Demis Hassabis
Hannah wraps up the series by meeting DeepMind co-founder and CEO, Demis Hassabis. In an extended interview, Demis describes why he believes AGI is possible, how we can get there, and the problems he hopes it will solve. Along the way, he highlights the important role of consciou ... Show More
30m 28s
<p>Here is my episode with Demis Hassabis, CEO of Google DeepMind</p><p>We discuss:</p><p>* Why scaling is an artform</p><p>* Adding search, planning, & AlphaZero type training atop LLMs</p><p>* Making sure rogue nations can't steal weights</p><p>* The right way to align superhum ... Show More