logo
episode-header-image
Mar 2025
1h 17m

#474 Resistant Hypertension the Next Fro...

The Curbsiders Internal Medicine Podcast
About this episode
Treat Hypertension Like No Doctor Has Ever Treated Hypertension Before

Treating hypertension never gets boring. Learn about emerging therapies and how to continue to tackle this common diagnosis like a pro.  Dr. Jordy Cohen (@jordybc.bsky.social) leads us through her approach to keeping the BP where it should be (University of Pennsylvania).

Claim CME for this episode at curbsiders.vcuhealth.org!

Patreon | Episodes | Subscribe | Spotify | YouTube | Newsletter | Contact | Swag! | CME

Show Segments

  • 00:00 Introduction and Current Interests
  • 01:55 Understanding Hypertension
  • 11:59 Blood Pressure Measurement Techniques
  • 19:58 Treatment Goals and Guidelines for Hypertension
  • 30:02 Managing Resistant Hypertension and New Treatments
  • 36:00 Exploring GLP-1 Agonists and Blood Pressure Benefits
  • 39:06 Aldosterone Synthase Inhibitors: A New Hope
  • 42:00 Innovative Approaches: Small Interfering RNAs in Hypertension
  • 47:06 Renal Denervation: A Controversial Procedure
  • 55:01 Understanding Resistant Hypertension and Testing Protocols

Credits

  • Writer and Producer: Deborah Gorth MD, PhD
  • Show Notes: Ben Furman and Deborah Gorth MD, PhD
  • Cover Art and Infographic: Deborah Gorth MD, PhD and Meryl Gorth RD, MPH
  • Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP   
  • Reviewer: Sai Achi MD, MBA, FACP
  • Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
  • Technical Production: PodPaste
  • Guest: Jordana Cohen MD, MSCE

Disclosures

Dr. Jordana Cohen and The Curbsiders report no relevant financial disclosures. 


Sponsor: Factor

Eat smart with Factor. Get started at factormeals.com/factorpodcast and use code FACTORPODCAST to get 50% off your first box plus free shipping. 

Sponsor:
CME Meeting 

Visit www.CMEmeeting.org/curbsiders to save 30% on all online courses and live webcasts with promo code CURB30.

Sponsor: Panacea Financial

Explore financial solutions designed to make your life better at panaceafinancial.com
Up next
Yesterday
500th Ep Bonus AMA: Diabetes Meds, AI in Medicine, Thyroid Antibodies, Sleep Meds, Top 5 Lists, Favorite Failures, and More!
In this bonus episode, Matt and Paul answer Patreon listener questions on various topics, including the role of AI in medicine, concerns about antibiotics and their impact on health, insomnia treatments, thyroid health, reflections on career burnout and more. They also share pers ... Show More
49m 22s
Oct 6
#500: COPD Update with Cyrus Askin
GOLD Updates, Novel Treatments, and Managing Comorbidities in COPD Care Level up your COPD care with practical, evidence-based strategies. Learn how to confirm airflow obstruction with spirometry (and use LLN/Z-scores thoughtfully), stage patients with the A/B/E framework, and bu ... Show More
1h 22m
Sep 29
REBOOT: #460 Heart Failure with Preserved Ejection Fraction
We have a classic episode for you. Preserve your sanity while treating heart failure with preserved ejection fraction. Dr Michelle Kittleson @MKittlesonMD (Cedars Sinai) illuminates this confounding cardiac condition. Sponsors Sponsor: FIGS Curbsiders listeners can get 15% off. J ... Show More
48m 57s
Recommended Episodes
Sep 19
193 - Elevate Your Guideline Knowledge, Not Your BP: The New 2025 Hypertension Guidelines
In this episode, we review the newly published 2025 ACC/AHA hypertension guidelines. Key Concepts Instead of the Pooled Cohort Equations (PCE) from 2013, the 2025 hypertension guidelines recommend a new risk equation called PREVENT, which incorporates new risk factors and does no ... Show More
35m 7s
Apr 2023
Dr Joseph Radich | How to Fix a Broken Sick Care System, Cutting Edge Health Bio-Hacks, Reducing High Blood Pressure & More! KKP: 573
Today, I am blessed to have Dr Joseph Radich. Dr Radich founded R3 Health, a safe and trustworthy VIP experience designed to solve its members' health, medical, and lifestyle problems. They believe that individualized healthcare is the key to achieving optimal and balanced wellne ... Show More
58m 40s
Sep 12
Sep 12 2025 This Week in Cardiology
More from ESC including: Valvular HD guidelines, a new drug class for HTN, myosin inhibition in HCM, vericiguat, and digoxin are the topic discussed by John Mandrola, MD. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit ... Show More
31m 5s
Sep 2024
Inside Congress’s Mission to Combat Chronic Disease | Rep. Vern Buchanan
What if the key to fixing our broken healthcare system lies within Congress? On this episode of “The Doctor’s Farmacy,” I sit down with U.S. Representative Vern Buchanan to tackle one of the biggest crises facing our country: the rise of chronic disease and its staggering economi ... Show More
43m 32s
Oct 2024
110. Dr. Aseem Malhotra: High Cholesterol Is NOT Killing You & Here's The Science
The shocking truth about cholesterol and heart disease that Big Pharma doesn't want you to know! In this explosive episode of Ultimate Human podcast, host Gary Brecka sits down with renowned cardiologist Dr. Aseem Malhotra to uncover the startling truth about cholesterol, heart d ... Show More
16m 33s
Nov 2024
Recap: Boost health by defeating stress | Dr. Rangan Chatterjee
Stress can come from any direction. Mounting deadlines at work, a romantic tiff at home, even something as simple as missing our bus can send our brain and body into a state of tension. We all experience this, it’s nothing new. However, our failure to manage this stress could be ... Show More
15m 25s
Jan 2025
406. Journal Club: The BPROAD Trial with Dr. Keith Ferdinand
Join CardioNerds co-founder Dr. Daniel Ambinder, episode lead Dr. Nidhi Patel, and expert faculty Dr. Keith Ferdinand as they discuss the BP ROAD trial. The BP ROAD trial randomized 12,821 patients 50 years of age or older with type 2 diabetes, elevated systolic blood pressure, a ... Show More
26m 41s
Apr 2025
Next-Generation Patient Access to Food, Medicine, and Lifestyle Programs | TWIRx
In this thought-provoking episode of This Week in Pharmacy, I am joined by three powerhouse leaders from health innovation: Dr. Alex Ding (Humana), Dr. Marc Watkins (Kroger Health), and Brian Urban (Best Buy Health). Together, they explore the next generation of patient access—wh ... Show More
49m 26s