Dr Alessandra Ferrajoli (University of Texas MD Anderson Cancer Center, US) provides an in-depth cumulative review of hypertension management in patients with Chronic Lymphocytic Leukemia (CLL) and other hematologic malignancies treated with Acalabrutinib. This podcast explores the mechanisms, incidence and clinical implications of treatment-related hypertension, offering evidence-based strategies to optimise cardiovascular care for this patient population.