In this episode, my guest is Dr. Thomas Wood, a UK-trained M.D. with a Ph.D. in physiology and neuroscience. He is a professor of pediatrics and neuroscience at the University of Washington. We discuss how both physical and mental challenges can enhance cognitive function in the short and long term. We also examine the crucial roles of nutrition, sleep, and ... Show More
May 27
How to Think Clearly in an Age of Distraction | Sam Harris
In this episode, I sit down with Dr. Sam Harris to discuss how attention, mindfulness, and clear thinking shape performance. We start by separating intelligence from wisdom, then look at how modern technology is rewiring our attentional capacity — including which tools enhance co ... Show More
2h 28m
May 13
Intense Exercise & Potential Heart Damage (aka Athlete's Heart)
In this episode, I cover "athlete's heart" — the paradox where the same cardiovascular adaptations that make endurance athletes exceptional can also mimic, and sometimes mask, real risk. I trace the history of what’s now known as exercise-induced cardiovascular remodeling (EICR), ... Show More
1h 44m
Apr 29
Hardship, Resilience & Competing at the Highest Level | Ken Rideout
In this episode, I sit down with Ken Rideout — author, elite masters marathoner, and one of the most compelling people I've ever had on the show — to discuss his journey from a difficult childhood and decade-long opioid addiction to becoming the Masters (50+) Marathon World Champ ... Show More
2h 34m
Sep 2024
How to Improve Memory & Focus Using Science Protocols | Dr. Charan Ranganath
In this episode, my guest is Dr. Charan Ranganath, Ph.D., professor of psychology and neuroscience at the University of California, Davis, and a world expert on the neuroscience of memory. We discuss how memory works, what causes diseases of dementia like Alzheimer’s, and science ... Show More
2h 39m
Sep 2024
Natural Ways to Prevent Alzheimer's and Boost Brain Health with Dr. Heather Sandison : 1199
<p>In this episode of <em>The Human Upgrade</em>, Dave Asprey and Dr. Heather Sandison discuss actionable strategies for optimizing brain health and longevity. Dr. Sandison explains how lifestyle changes, including diet, oral hygiene, and sleep, can help prevent cognitive decline ... Show More
1h 2m
Feb 2025
The truth behind memory loss - and how to stop it with exercise | Dr. Wendy Suzuki
We spend so much time focusing on how exercise changes our bodies - burning calories, building muscle, shedding fat. What if the most important transformation is happening where you can’t see it? Hidden inside your skull, your brain is changing with every step, squat, and sprint. ... Show More
1h 8m
Jul 2024
4 Experts Share Tips to Boost Brain Health, Focus, and Thinking : 1183
<p>In this special episode of<em> The Human Upgrade</em>, you will gain insights from four experts on brain health, memory, attention, and cognitive enhancement. </p><p><strong>Dr. Daniel Amen</strong>, a renowned psychiatrist and brain health expert, discusses the importanc ... Show More
1h 2m
Feb 2025
#99: Neuroplasticity: The Brain's Superpower - Philippe Douyon, MD
This episode features Dr. Philippe Douyon, a board-certified neurologist specializing in neuroplasticity, brain health, and cognitive resilience. We discuss the brain's ability to adapt and reorganize, challenging misconceptions like the belief that cognitive change is limited to ... Show More
1h 9m
Nov 2024
How to Improve at Learning Using Neuroscience & AI | Dr. Terry Sejnowski
In this episode, my guest is Dr. Terry Sejnowski, Ph.D., professor of computational neurobiology at the Salk Institute for Biological Studies. He is world-renowned for exploring how our brain processes and stores information and, with that understanding, for developing tools that ... Show More
2h 34m