logo
episode-header-image
Jan 2025
53m 8s

326: I Have One Word For You: PETase!

VINCENT RACANIELLO
About this episode

TWiM explores the discovery of microbial enzymes, PETases, that can degrade ubiquitous plastics, and how exogenous peptidoglycan is a danger signal to trigger biofilm formation.

Hosts: Vincent Racaniello, Michael Schmidt, Michele Swanson.

Guest Mark O. Martin.

Subscribe to TWiM (free) on Apple Podcasts, Spotify, Android, RSS, or by email.

Become a patron of TWiM.

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Links for this episode

Send your microbiology questions and comments (email or recorded audio) to twim@microbe.tv

Up next
Nov 8
344: Ant Yogurt and Fine Chocolate
TWiM reveals the bacteria, acids, and enzymes behind yogurt made with ants, and a defined set of microbes that reproduces attributes of fine flavor chocolate fermentation Hosts: Vincent Racaniello, Michael Schmidt, and Petra Levin Guest: Mark O. Martin Become a patron of TWiM. Li ... Show More
1h 6m
Oct 25
343: Nucleotides to the Defense
TWiM explores two different ways that bacteria defend against phages through the synthesis of cyclic nucleotides. Hosts: Michael Schmidt and Mark O. Martin Become a patron of TWiM. Links for this episode: Decoy cyclic nucleotides in phage defense (Nature) CRISPR defense with nucl ... Show More
43m 57s
Oct 11
342: The Microbiome, Pancreatic Cancer, and Sleep Quality
TWiM explains studies that show that the oral bacterial and fungal microbiome are risk factors for pancreatic cancer, and the gut microbiome and pyruvate metabolism of older adults are a link between sleep quality and frailty. Hosts: Vincent Racaniello, Michael Schmidt, and Miche ... Show More
53m 37s
Recommended Episodes
Jun 2017
MWV 111 (audio only) TWiM live at Microbe: Rigor, lotteries, and moonshots
At Microbe 2017 in New Orleans, the TWiM team speaks with Arturo Casadevall about his thoughts on the pathogenic potential of a microbe, rigorous science, funding by lottery, and moonshot science. Hosts: Vincent Racaniello, Michael Schmidt, Elio Schaechter and Michele Swanson. Gu ... Show More
1h 16m
Sep 26
The Dead Composer Whose ‘Brain’ Still Makes Music
In a hauntingly innovative exhibit, brain cells grown from the late composer Alvin Lucier’s blood generate sound. Set in a museum in Perth, Australia, the installation blurs the line between art and neuroscience. Host Rachel Feltman and associate editor Allison Parshall explore t ... Show More
25m 25s
May 2025
Do Mitochondria Talk to Each Other? A New Look at the Cell’s Powerhouse
Mitochondria are known as the powerhouse of the cell—but new research suggests they might be far more complex. Columbia University’s Martin Picard joins Scientific American’s Rachel Feltman to explore how these tiny organelles could be communicating and what that might mean for e ... Show More
27m 4s
Jul 2025
What Does an Ailing Coral Reef Sound Like?
Sick coral reefs are visually striking—bleached and lifeless, far from the vibrancy we’ve come to expect. But what does an unhealthy coral system sound like? In this rerun, conservation bioacoustics researcher Isla Keesje Davidson tells Science Quickly all about the changing soun ... Show More
16m 51s
Jan 2025
Combatting Climate Anxiety through Community Science
It’s easy to feel overwhelmed with the news these days and to fear for the future. What if you could interrupt doomscrolling and contribute to conservation at the same time? That’s the idea behind programs like Adventure Scientists, eBird and iNaturalist. Guest Gregg Treinish, fo ... Show More
14m 34s
May 2025
TWiV Special: A shot of HepB with Thomas Tu
From the 2024 International Hepatitis B virus meeting in Chicago IL, Rich Condit speaks with Thomas Tu about his experiences as a both a HepB scientist and patient. Host: Rich Condit Guest: Thomas Tu Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for ... Show More
25m 11s
Oct 6
Enceladus’s Alien Ocean, Ancient Fungi and the Flavor of Influenza
Saturn’s moon Enceladus reveals complex organic molecules that could hint at extraterrestrial life. Researchers also uncover fungi’s ancient reign over Earth and warn that second COVID infections may pose greater risks to young people. Plus, ants ferment yogurt, and flu detection ... Show More
9m 47s
Feb 2025
Hors-série : Synthèse vocale, clonage de voix... L'intelligence artificielle va-t-elle nous couper la parole ?
Les comédiens de doublage sur le point d'être doublés ? Eh oui, le clonage vocal est en marche, et les voix mythiques de la VF ne sont plus à l’abri des algorithmes. Les chanteurs et les podcasteurs non plus, gloups. Du désastreux doublage IA de Sylvester Stallone à la promesse d ... Show More
48m 28s
Feb 2025
Exploring the Hidden Life in the Air around Us with Carl Zimmer
Scientists now agree that COVID spreads via airborne transmission. But during the early days of the disease, public health officials suggested that it mainly did so via close contact. The subsequent back-and-forth over how COVID spread brought science journalist Carl Zimmer into ... Show More
16m 47s
Nov 12
How Science Can Hack Flavor
Will eating mint cancel out the feeling of spice in your mouth? How do you manipulate aroma compounds to mimic the taste of lemon? When it comes to the science of flavor, there is no shortage of questions to ask. On this episode, Dr. Samantha Yammine is joined by renowned flavor ... Show More
30m 20s