Listener feedback, multiple studies in AF ablation,
a DANISH trial substudy of ICDs in NICM, and more data on eye complications of GLP-1 agonists are the topics John Mandrola, MD, covers in this week’s podcast.
This podcast is intended for healthcare professionals only.
To read a partial transcript or to comment, visit:
https://www.medscape.com/twic
I. CCTA Feedback
- Foy meta-analysis https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2655243
- DANCAVAS https://www.nejm.org/doi/full/10.1056/NEJMoa2208681
II. Listener Feedback on my negative take of the OPTION Trial.
- Option trial https://www.nejm.org/doi/pdf/10.1056/NEJMoa2408308
- My Preview https://www.medscape.com/viewarticle/mandrola-previews-option-trial-most-worrisome-study-aha-2024-2024a1000kmz
- 4 Reasons to Question Percutaneous Left Atrial Appendage Closure After AF Ablation
- https://www.medscape.com/viewarticle/4-reasons-question-percutaneous-left-atrial-appendage-2024a1000l0u
III. AF Ablation
PVI Add-Ons Provide Better Control of Persistent AF
https://www.medscape.com/viewarticle/pvi-add-ons-provide-better-control-persistent-af-2024a1000lcm
- VENUS https://jamanetwork.com/journals/jama/fullarticle/2772281
- PROMPT AF https://jamanetwork.com/journals/jama/fullarticle/2826710
- STAR AF 2 https://www.nejm.org/doi/full/10.1056/NEJMoa1408288
- CRRF-PeAF https://pmc.ncbi.nlm.nih.gov/articles/PMC9241129/
- CAVAC trial https://doi.org/10.1161/CIRCEP.124.012917
- CRRF-PeAF from multiple centers in Japan (not published)
IV. DANISH Trial Substudy
- Danish Trial Substudy https://www.ahajournals.org/doi/epdf/10.1161/CIRCULATIONAHA.124.071777
- Danish Main https://www.nejm.org/doi/full/10.1056/NEJMoa1608029
- MADIT-2 EF Substudy https://doi.org/10.1016/S0002-9149(01)01729-5
- SCD-HeFT subgroup https://www.nejm.org/doi/full/10.1056/NEJMoa043399
- Appraisal of ICD to Prevent SCD https://doi.org/10.1016/j.jacc.2008.05.058
V. Eye disease and GLP-1 Agonists
Jul 26, 2024 This Week in Cardiology Podcast
https://www.medscape.com/viewarticle/1001384
- Semaglutide vs No Semagutide and Eye Disease https://link.springer.com/epdf/10.1186/s40942-024-00620-x
- Semaglutide vs SGLT- Inhibitors and Eye Disease https://www.medrxiv.org/content/10.1101/2024.12.09.24318574v1.full-text
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