This week, we round out our discussion regarding AML induction, this time focusing on the treatment options in the first line setting. We go through the various options, the dosing strategies, and the data behind them.
Be sure to check out parts one and two of this three-part induction discussion, as we continue to build on these concepts! Also, if you hav ... Show More
Oct 7
Episode 166: Pancreatic Cancer Series, Pt. 1 – Biology, Diagnosis, and Staging
This week we kick off a brand-new series on pancreatic cancer, starting with the fundamentals. Using the case of a 68-year-old man with painless jaundice, weight loss, and new-onset diabetes, we cover the epidemiology and sobering survival statistics of pancreatic ductal adenocar ... Show More
28m 52s
Sep 23
Episode 165: CLL Updates Series, Pt. 2 – Relapsed/Refractory in 2026
This week we wrap up our two-part CLL update by turning to relapsed and refractory disease. We pick up with the 68-year-old man from Part 1, now a year out from frontline therapy and showing signs of relapse. We cover when relapse actually needs treatment, the history of BTK inhi ... Show More
22m 22s
Sep 16
Episode 164: CLL Updates Series, Pt. 1 – Frontline Therapy in 2026
This week we kick off a two-part update to our CLL series, covering what has changed in frontline management since our original episodes. Using the case of a 68-year-old man with newly diagnosed, symptomatic CLL, we revisit the essential steps before treatment: confirming an indi ... Show More
26m 2s
May 2022
Acute Myeloid Leukemia (AML)
<p>Today’s episode is all about AML (acute myeloid leukemia), including the usual presentation, diagnostic work-up, risk stratification (and tricks to remember these), molecular testing, and treatment options for first-line, as well as relapsed/refractory disease.</p>
15m 18s
Oct 2024
254. Months of Monocytosis – An approach to CMML
Send us Fan MailIn this episode, we discuss the clinical presentation, work-up, and treatment of CMML. Our medicine minute discusses emerging evidence on the use of ruxolitinib for CMML treatment. Written by: Dr. Elliot Smith (Internal Medicine Resident)Reviewed by: Dr. Stephanie ... Show More
17m 17s
Aug 2021
Latest Research on the Intensity of AML Therapy in Older Patients, Platelets and T cell Activity in Sepsis, and Genotyping for CNS Lymphoma
In this week's episode, we’ll start by reviewing an intriguing study that, while not randomized, calls into question whether less-intensive induction therapies provide a survival or quality of life benefit in older patients with AML. Next, we will review the somewhat surprising f ... Show More
19m 21s
May 2022
S1 Episode 2: Frontline Therapy for Multiple Myeloma
Joseph Mikhael, MD, and Peter Voorhees, MD, discuss frontline therapy for multiple myeloma and new options for both transplant-eligible and transplant-ineligible patients. Relevant disclosures can be found with the episode show notes on Medscape.com (https://www.medscape.com/view ... Show More
23m 37s