In this week's episode, we’ll start by reviewing an intriguing study that, while not randomized, calls into question whether less-intensive induction therapies provide a survival or quality of life benefit in older patients with AML. Next, we will review the somewhat surprising findings from human and mouse model studies demonstrating that platelets downregu ... Show More
Sep 2024
Episode 116: AML Series, Pt. 2 - MDS/AML Diagnosis and Risk Stratification
<p>In this week’s episode, we discuss the diagnostic criteria and risk stratification for myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML), building on our discussion from last week. Also, if you have not done so, please do check out our hemepath series to ensure y ... Show More
31m 56s
Oct 2024
Episode 119: AML Series, Pt 5 - AML Induction: Options for Upfront Therapy
<p>This week, we round out our discussion regarding AML induction, this time focusing on the treatment options in the first line setting. We go through the various options, the dosing strategies, and the data behind them. </p><p>Be sure to check out parts one and two of this thre ... Show More
26m 39s
Oct 2024
Episode 117: AML Series, Pt. 3 - AML Induction: Definitions and Overview
<p>In this week’s episode, we start our three-part discussion on AML induction, this week focusing on key definitions and an overview of treatment. Also, if you have not done so, please do check out our hemepath series to ensure you can more easily follow along with this conversa ... Show More
27m 22s
Oct 2024
Episode 120: AML Series, Pt 6 - AML Consolidation: Therapeutic Approaches
<p>This week, we move to our next phases of therapy for AML, which are consolidation and maintenance. Be sure to check out our prior episodes for a discussion on initial workup and how we incorporate recurrent genetic abnormalities into how we think about AML. Check out figure 1 ... Show More
32m 29s
Sep 2024
Episode 115: AML Series, Pt. 1 - CHIP, CCUS, ICUS, oh my!
<p>This week, we kick off a new series focusing on myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). In this first episode, we discuss the alphabet soup of premalignant hematologic conditions including CHIP, CCUS, and ICUS, before moving onto MDS and AML in future ... Show More
35m 14s
<p class="" style="white-space:pre-wrap;">In today’s episode, we discuss how to approach AML treatment for patients who are unfit for intensive therapy.</p><p class="" style="white-space:pre-wrap;">Episode contents: </p><p class="" style="white-space:pre-wrap;">- How do we assess ... Show More
