logo
episode-header-image
Aug 2024
28m 3s

Cancer vaccine trials and planning for c...

Bbc Radio 4
About this episode

Trials of a cancer 'vaccine' have begun and presenter James meets Steve, one of the first patients to trial the new treatment, Steve remembers his shock at being diagnosed with colorectal cancer in his 40s and tells the story of how he became involved in this pioneering research into tackling cancer.

The vaccine is based on the same mRNA technology as the Pfizer-BioNTech COVID-19 vaccine and James heads to the University of Cambridge to find out how the early work into cancer vaccines became the foundation for the rapid rollout of the covid vaccine.

In the lab, molecular biologist Dr Anne Willis and immunologist Dr James Thaventhiran explain how the vaccine is personalised to target the unique make-up of an individual patients' cancer cells, and how if the trials are successful they could open the door to mRNA treatments being used to treat a wide range of diseases.

Also, Imperial College London cyber security researcher Dr Saira Ghafur joins James in the studio to explain why healthcare is a growing target for cyber attackers and how we can prepare for the next one because, as Saira says, it really is a case of "when" not "if".

Presented by James Gallagher Produced by Tom Bonnett with Hannah Robins Assistant Producer: Katie Tomsett Editor: Holly Squire

Up next
Jul 28
Staying fit in the heat and do we need electrolytes?
We’ve had two heatwaves already this summer with warnings that even young and healthy people should rethink their fitness routines in the heat. So how can we keep exercising when it’s so hot you barely want to move? James chats with physiologist Damian Bailey from the University ... Show More
27m 48s
Jul 21
Could we eliminate cervical cancer?
Earlier this summer, there was some incredible progress in cervical cancer. Women who have been vaccinated against the human papillomavirus (HPV) now have an almost zero chance of dying from cervical cancer before the age of 30. But does that mean women will no longer need cervic ... Show More
27m 49s
Jul 14
Could CAR-T therapy transform autoimmune disease?
An experimental treatment to “reset” the immune systems of people with autoimmune disease is showing transformative results in early trials. James visits the NIHR Clinical Research Facility in Manchester to meet Kathy. She was diagnosed with lupus just after the birth of her baby ... Show More
27m 56s
Recommended Episodes
May 2023
A cancer vaccine?
Dr. Vinod Balachandran explains how he and his colleagues successfully treated pancreatic cancer with bespoke mRNA vaccines. Science journalist Charles Graeber says this could be cancer’s “penicillin moment.” This episode was produced by Avishay Artsy, edited by Matt Collette, fa ... Show More
26m 6s
Sep 2021
The future of vaccines
The founders of German biotechnology company BioNTech were researching how to fight cancers using messenger RNA, "the unloved cousin of DNA", when covid-19 first appeared and they realised mRNA could be used to make a vaccine for the disease. Financial Times journalist Joe Miller ... Show More
17m 28s
Jul 2020
Demystifying the Vaccine
A recent vaccine trial from Oxford University shows promising preliminary results, suggesting the vaccine can produce immune responses that may protect people against infection. Dr. Sanjay Gupta spoke with Dr. Barney Graham, the deputy director of the Vaccine Research Center at t ... Show More
11m 17s
Dec 2020
The mRNA Breakthrough
How do you fight a pandemic? With cutting edge technology. Two of the new Covid-19 vaccines applying for FDA approval rely on a novel approach that uses mRNA to turn the human body into an internal vaccine factory. CNN Chief Medical Correspondent Dr. Sanjay Gupta talks to mRNA re ... Show More
9m 12s
Jun 2020
People Are Volunteering To Be Exposed To The Coronavirus...For Science
In this episode, Maddie Sofia talks with Invisibilia's Alix Spiegel about the bioethics of conducting human challenge trials with the aim of producing a viable coronavirus vaccine. We hear from James Kublin, a clinical health professor in the Department of Global Health at the Un ... Show More
10m 50s
Nov 2019
Ep. 51 – New Cancer Therapies & Targeting Cancer Biology
Join Lebaron (Lee) Agostini and Connor Wander in our FIRST VIDEO episode! This episode is all about Cancer Biology. Lee studies experimental cancer therapies for pancreatic cancer. New cancer therapies called combination or synergystic cancer therapies use multiple drug types to ... Show More
1h 30m
Jul 2024
Can light emitting bandages treat cancer?
A special episode from this year’s annual Royal Society Summer Exhibition in London, with Claudia Hammond joined by BBC health and science correspondent, James Gallagher, to take a look at a range of new health research. The exhibitions include a look at how special forms of UV l ... Show More
26m 29s
Feb 2025
A vaccine for cancer
There's been a breakthrough in cancer research! Hear all about it and learn some vocabulary with Neil and Beth. Find a full transcript, worksheet and interactive quiz for this episode at: https://www.bbc.co.uk/learningenglish/english/features/6-minute-english_2025/ep-250227Check ... Show More
6m 31s
Oct 2025
TWiV 1265: mRNA vaccines make cancer treatment great again
<p>TWiV explains studies showing that SARS-CoV-2 mRNA vaccines improve life span of cancer patients on checkpoint immunotherapy, and broad immunity conferred by a vaccine central in A(H5) influenza antigenic space.</p> <div class="fluid-width-video-wrapper">Hosts: <a title="" hre ... Show More
1h 51m