logo
episode-header-image
Aug 26
28m 10s

Potential Break Through in Dementia Trea...

Bbc Radio 4
About this episode

Dementia is now the UK’s leading cause of death - but could a vaccine one day help prevent it? New data from Wales suggests the shingles vaccine is linked to a 20% lower risk of developing dementia in later life, adding to evidence that viral infections can influence brain health.

Dr. Pascal Geldsetzer, Assistant Prof of Medicine at Stanford University discusses his findings and the further evidence required to prove this link, along with Prof Tara Spires-Jones, Group Leader in the UK Dementia Research Institute.

The UK has begun using the world’s first gonorrhoea vaccine - though it was originally developed for meningitis. With antibiotic-resistant strains increasing, we speak to Dr Suneeta Soni about why gonorrhoea has been so hard to target with vaccines.

At the Bristol Robotics Lab, engineers are creating devices to support mobility in older age. James meets Jonathan Rossner and tries out “The Right Trousers” - an inflatable exoskeleton designed to help people walk and to strengthen their muscles.

Presenter: James Gallagher Producers: Debbie Kilbride, Tom Bonnett & Minnie Harrop Editor: Ilan Goodman Production coordinator: Ishmael Soriano This episode was produced in partnership with The Open University.

Up next
Sep 2
The Revolution in Cystic Fibrosis Care That is Changing Lives
In 1964, the future for children born with Cystic Fibrosis was grim - most faced a life cut tragically short. Today, the majority of people living with CF in the UK are adults, a testament to extraordinary medical progress.We meet Annabelle who lives with Cystic Fibrosis, and onc ... Show More
28m 5s
Aug 19
Is it safe to give kids melatonin?
More and more parents are using melatonin to help their children sleep - but there is little research on the long-term effects. So, what do we know about the risks and is it ok to give it to children as an aid to help sleep?James chats to Paul Gringras, professor of children’s sl ... Show More
28m 6s
Aug 12
Can we reverse rising drug deaths?
Drug-related deaths are at their highest levels in England and Wales since records began 30 years ago.Scotland has had the highest number of drug deaths in Europe for at least seven years. And the UK has even seen opioid-related deaths surpass the number of people dying in road t ... Show More
28m 13s
Recommended Episodes
Oct 2
What does caffeine do to our bodies?
Sweet, caffeinated energy drinks are in the headlines again as the UK Government says it wants to ban under 16s from buying them. Some can contain the equivalent caffeine as 2 to 4 espressos. James Betts, Professor of Metabolic Physiology at the University of Bath, explains the s ... Show More
28m 21s
Feb 2024
PT483 – Dr. Kate Pate – Traumatic Brain Injuries, the Gut Microbiome, and the Potential of Psychedelics as Anti-Inflammatory Agents
In this episode, Joe interviews Dr. Kate Pate: Ph.D. neurophysiologist; Founder and CEO of Coruna Medical; founding board member of the Psychedelic Medicine Association; and Founder of The Way Back, a company that will provide education and coaching services related to military, ... Show More
56m 13s
Sep 4
What’s the evidence for vaccines?
US Health Secretary Robert F Kennedy Jr announced plans this week to cancel $500 million dollars of funding for mRNA vaccine development. The research was focusing on trying to counter viruses that cause diseases such as the flu and Covid-19.Marnie Chesterton is joined by Profess ... Show More
28m 11s
Apr 2025
Tackling bias in health
Bias in the way medical research is carried out means that new medicines for diseases such as cancer – as well as the tools used to diagnose patients with some conditions – are disproportionally tested on people of European heritage. This can lead to those not represented in the ... Show More
23m 18s
Jun 2024
Why medical error is not the third leading cause of death in the US
The claim that medical error is the third leading cause of death in the US has been zooming around the internet for years. This would mean that only heart disease and cancer killed more people than the very people trying to treat these diseases. But there are good reasons to be s ... Show More
9m 13s
Apr 2024
PT500 – Shulgin Farm and the Future of Psychedelic Drug Development, with Paul F. Daley, Ph.D.
In this episode, Joe interviews Paul F. Daley, Ph.D., who worked with Sasha Shulgin in his lab for the last seven years of his life, helping him finish (and co-authoring) "The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds." He is now the co-founder, ... Show More
36m 1s
Nov 2023
#24 A week in the name of medicines safety – part 1
To mark #MedSafetyWeek, which takes place from 6–12 November, we’re releasing a special two-part episode on pharmacovigilance communication campaigns. In this first part, we speak to Mitul Jadeja from the Medicines and Healthcare products Regulatory Agency in the UK about under-r ... Show More
27m 9s
Jan 2025
Prehabilitation before surgery, alcohol's impact on clinical care, and life after a cardiac arrest
Exercise and a better diet, prior to surgery, can improve outcomes. Daniel McIsaac, a professor of anaesthesiology from the University of Ottowa and lead author of that research, joins us to talk about getting those results into practice. Julia Sinclair, professor of addiction ps ... Show More
40m 40s
Jul 2024
Review of the Nursing and Midwifery Council, Black market weight loss drugs, Composer Undine Smith Moore
Former Chief Prosecutor Nazir Afzal speaks to Nuala McGovern about his independent culture review of the Nursing and Midwifery Council, which is the independent regulator for nurses and midwifes in the UK. The report is highly critical, finding that a "dysfunctional culture" at t ... Show More
55m 40s
Apr 2025
Why Australians Live 7 Years Longer Than Americans with Dr. Adrian Cois
On this month's installment of our Longevity Series, WHOOP Global Head of Human Performance, Principal Scientist, Dr. Kristen Holmes, sits down with Dr. Adrian Cois. Dr. Cois is an Australian-born Emergency Physician and Assistant Professor of Emergency Medicine, currently practi ... Show More
47m 15s