In the fed state, glucose is used by almost all the cells in the body to generate energy. But even when we are not fueling it with food, our bodies still run well, such as during sleep. Gluconeogenesis is the process of synthesizing glucose from noncarbohydrate precursors. The major substrates (substances that enzymes act on) are the glucogenic amino acids, ... Show More
Oct 2017
The Pentose Phosphate Pathway | MWM Energy Metabolism Cliff Notes #27
The pentose phosphate pathway provides a deep look into a stunning array of essential roles for glucose. In it, glucose becomes the source of NADPH, used for antioxidant defense, detoxification, recycling of nutrients like vitamin K and folate, and the anabolic synthesis of fatty ... Show More
10m 34s
Sep 2017
Energy Status Regulates Glycolysis |MWM Energy Metabolism Cliff Notes #21
This lesson covers the regulation of glycolysis. The principle regulation occurs at phosphofructokinase, which guards the gate to the first irreversible, committed step to burn glucose for energy. What governs it? Energy. If you need more ATP, you burn more glucose; if you don't, ... Show More
11m 35s
Jul 2021
A question on urinary lactate, pyruvate, and Krebs Cycle metabolites | Masterjohn Q&A Files #229
Please consider supporting my work by making a purchase using these links at one of my affiliates: https://chrismasterjohnphd.com/foursigmatic, https://chrismasterjohnphd.com/paleovalley, https://chrismasterjohnphd.com/seekinghealth, https://chrismasterjohnphd.com/ancestralsupple ... Show More
11m 51s
Oct 2025
The Pancreas: Our Most Underrated Metabolic Organ & Why Its Health is Vital
📢 Dr. Bikman’s Community & Coaching Site, Insulin IQ: https://insuliniq.com📢 Become an Insider, Ben’s website: https://www.benbikman.comIn this episode of Metabolic Classroom, Ben Bikman takes a detailed look at the pancreas, a small but mighty organ with two major roles—endocr ... Show More
21m 31s
Jun 2023
Dr Richard Johnson | Why it’s Fructose (NOT GLUCOSE) That Drives Insulin Resistance and Metabolic Disease KKP: 602
Today, I am blessed to have here with me Dr. Richard Johnson. He is a professor of medicine at the University of Colorado and is a clinician, educator, and researcher. He is board-certified in internal medicine, infectious diseases, and kidney disease and is the founding editor o ... Show More
1h 2m