TWiPO #70 - Dr. Joshua Rubin talks about...

In this episode Dr. Timothy Cripe and Dr. Brenda Weigel are joined by FDA's Dr. Nicole Drezner, pediatric oncologist and the Deputy Division Director of the Division of Oncology 2 who led the FDA review and publication on the approval of DFMO. Listen in on the discussion surround ... Show More

Dr. Luca Szalontay,  Assistant Professor of Pediatrics at Columbia University Medical Center, discusses the work of Columbia's Initiative for Drug Delivery Innovation which is exploring new treatments for pediatric brain tumors utilizing Convection Enhanced Delivery and Focused U ... Show More

WATCH THE VIDEO WEBCAST HERE: https://youtu.be/ACFprGG10M0 In this episode, our host, Dr. Timothy Cripe from Nationwide Children’s Hospital, is joined by Dr. Seth Rotz - pediatric hematologist/oncologist and the Director of the Fertility Preservation Program at the Cleveland Clin ... Show More

I was invited to participate in the FDA roundtable on menopausal hormone therapy. I declined. In this episode, I’m going to tell you why. A brief history of the FDA Why there is a black box warning on all estrogen products Why the black box warning should be removed from all loca ... Show More

Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers, including breast, gastric, colorectal, and epithelial ovarian cancers. However, this receptor's complexity doesn't stop there. It has multiple subdomains and various responses to drugs, and the ... Show More

In this episode, Joe interviews Paul F. Daley, Ph.D., who worked with Sasha Shulgin in his lab for the last seven years of his life, helping him finish (and co-authoring) "The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds." He is now the co-founder, ... Show More

I had the pleasure of talking with Dr. Christina Rahm, who has an inspiring journey from a pharmaceutical executive to an advocate for integrating holistic health solutions with rigorous scientific methods. We dive into the impact of spirituality on wellness, the transformative p ... Show More

Radiothérapie interne vectorisée par 177Lu-PSMA-617 de l’adénocarcinome prostatique : principe et perspectives.Qu’est-ce que la radiothérapie interne vectorisée et quel est son intérêt dans le traitement du cancer prostatique ? Pour quel patient ce traitement est-il actuellement ... Show More

#206 Melissa and Jam address a listener's question about the FDA's reliability in approving products. They discuss the intersection of chemistry, government, and society, focusing on FDA's role in regulating food and drugs. The episode includes a deep dive into the historical tha ... Show More

When people were dying from AIDS in the 1980s and 90s, Congress found a way to expedite the drug approval process and saved countless lives. Established in 1992, the Accelerated Approval Program allows the FDA to speed approval of drugs for patients with serious and life-threaten ... Show More

On this week's episode of the pod, we are talking about a drug that's been available for decades but is suddenly being pulled from shelves: phenylephrine (something you've probably reached for when you've been congested). We bring on an expert, Dr. Mikkael Sekeres, a Professor of ... Show More

Editor’s Summary by Kirsten Bibbins-Domingo, PhD, MD, MAS, Editor in Chief, and Preeti Malani, MD, MSJ, Deputy Editor of JAMA, the Journal of the American Medical Association, for articles published from February 1-7, 2025. 

Melanoma is a commonly encountered, often metastatic, disease in canine patients. In this episode of Clinician’s Brief Partner Podcast, Dr. Beth invites Dr. Timothy Fan to share advice on the clinical management of melanoma in practice. Dr. Fans offers insights on staging, surgic ... Show More