In this episode, Robert J. Noecker, MD, reviews the role of preservatives, particularly benzalkonium chloride (BAK), in ophthalmic medications. While BAK effectively prevents bacterial growth, its inherent toxicity poses challenges with prolonged use, leading to symptoms associated with ocular surface diseases. Dr. Noecker emphasizes the importance of explor ... Show More
Jun 2024
Enhancing Patient Satisfaction through BAK-Free Solutions: Dr. Miriam Kolko's Vision for Preservative-Free Eye Care
In this episode, Miriam Kolko, MD, PhD, shares her vision for preservative-free eye care. Dr. Kolko strongly advocates for patient education regarding the benefits and limitations of preservative-free alternatives, encouraging tailored treatment strategies. Ultimately, she envisi ... Show More
12m 7s
Jun 2024
Unveiling the Paradox: BAK's Role in American Pharmaceuticals With Dr. Nate Radcliffe
In this episode, Nathan Radcliffe, MD, discusses the widespread use of benzalkonium chloride (BAK) in the US ophthalmic market. Dr. Radcliffe acknowledges concerns about its long-term effects, such as exacerbating dry eye and impacting the success of incisional glaucoma surgery. ... Show More
11m 24s
Jun 2024
The European Approach to Preservative-Free Pharmaceuticals: A Conversation With Dr. Anton Hommer
In this episode, Anton Hommer, MD, discusses the European perspective on adopting preservative-free pharmaceuticals, highlighting challenges like health care professionals’ reluctancy to change, diverse reimbursement systems, and higher costs. He compares single-use and multiuse ... Show More
11m 50s
May 2023
29: Hydroxychloroquine – Potentially toxic, potentially blinding
One of the side-effects for patients who take hydroxychloroquine, or chloroquine, can be retinal toxicity. The drug is usually taken to help treat rheumatic disorders, but around 7.5% of people who take hydroxychloroquine for over five years are thought to develop retinopathy. Th ... Show More
27m 59s
Mar 2023
Promethazine (Phenergan) Pharmacology Podcast
In this promethazine pharmacology podcast, I discuss its mechanisms of action, side effects, important drug interactions, and much more. Promethazine has anticholinergic and dopamine-blocking activity which contributes to the adverse effect profile as well as its efficacy. There ... Show More
15m 13s
Aug 2023
Isotretinoin Pharmacology Podcast
On this episode, I discuss isotretinoin pharmacology, side effects, drug interactions, and much more. The iPLEDGE program is in place to ensure that pregnant patients do not receive this medication. I discuss this in more detail on this episode. Sun sensitivity is an important ad ... Show More
11m 38s
Feb 2024
Outpatient Antibiotic Stewardship
Host: Darryl S. Chutka, M.D. [@chutkaMD] Guest: Kelsey L. Jensen, Pharm.D., R.Ph. Guest: Daniel Ilges, Pharm.D., R.Ph., BCIPD The appropriate use of antibiotics is important for a variety of reasons. It helps keep our patients safe, helps maintain antibiotic effectiveness in trea ... Show More
23m 2s
Jun 2023
Cefuroxime Pharmacology Podcast
On this episode, I discuss cefuroxime pharmacology, adverse effects, drug interaction, pharmacokinetics, and much more. Cefuroxime is a 2nd generation cephalosporin that binds Penicillin-binding proteins and prevents bacterial cell wall synthesis. Medications that create a higher ... Show More
13m 34s